CCL16/HCC-4/LEC Antibody (LEC66) [Alexa Fluor® 647]

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP2-34666AF647
    • Availability
      Product Discontinued

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CCL16/HCC-4/LEC Antibody (LEC66) [Alexa Fluor® 647] Summary

Immunogen
Recombinant human HCC-4 protein
Localization
Secreted (extracellular)
Specificity
Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelo-suppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES. Mainly expressed in liver, also found in spleen and thymus. Highly expressed in LPS- and IFN-gamma-activated monocytes, weakly in some lymphocytes, including natural killer cells, gamma-delta T-cells, and some T-cell clones. The ability of HCC-4 to markedly improve recognition of poorly immunogenic cells suggests that it could be an effective component of antitumor vaccines.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CCL16
Purity
Protein A purified
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Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Conjugate
Alexa Fluor 647
Format
Alexa Fluor 647 (A=650, E=668)
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Applications/Dilutions

Theoretical MW
11 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Alternate Names for CCL16/HCC-4/LEC Antibody (LEC66) [Alexa Fluor® 647]

  • C-C motif chemokine 16
  • CCL16/HCC-4
  • chemokine (C-C motif) ligand 16
  • Chemokine CC-4
  • Chemokine LEC
  • CKb12
  • HCC4
  • HCC-4
  • HCC-4Liver-expressed chemokine
  • LCC-1Lymphocyte and monocyte chemoattractant
  • LEC
  • liver CC chemokine-1
  • LMC
  • LMCSmall-inducible cytokine A16
  • monotactin-1
  • Mtn-1
  • NCC-4
  • NCC4IL-10-inducible chemokine
  • NCC-4ILINCK
  • new CC chemokine 4
  • SCYA16MGC117051
  • SCYL4
  • small inducible cytokine subfamily A (Cys-Cys), member 16

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Contact Information

Product PDFs

Bioinformatics

Gene Symbol CCL16
Entrez
Uniprot

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