CCL16/HCC-4/LEC Products

Description

LEC is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for lymphocytes and monocytes but not for neutrophils. This cytokine also shows a potent myelosuppressive activity and suppresses proliferation of myeloid progenitor cells. The expression of this gene is upregulated by IL-10. [provided by RefSeq]

Bioinformatics

Entrez	6360 Human
Uniprot	NM_004590 Human NP_004581.1 Human O15467 Human
Product By Gene ID	6360
Alternate Names	C-C motif chemokine 16 chemokine (C-C motif) ligand 16 Chemokine CC-4 Chemokine LEC CKb12 HCC-4Liver-expressed chemokine LCC-1Lymphocyte and monocyte chemoattractant LEC liver CC chemokine-1 LMCSmall-inducible cytokine A16 Monotactin-1 monotactin-1 Mtn-1 MTN-1 NCC4IL-10-inducible chemokine NCC-4ILINCK new CC chemokine 4 SCYA16MGC117051 SCYL4 small inducible cytokine subfamily A (Cys-Cys), member 16