CC Chemokine Receptor D6 Antibody

Western Blot: CC Chemokine Receptor D6 Antibody [H00001238-B02P] - Analysis of CCBP2 expression in transfected 293T cell line by CCBP2 polyclonal antibody. Lane 1: CCBP2 transfected lysate(42.24 KDa). Lane 2: Non-transfected lysate.

Flow Cytometry: CC Chemokine Receptor D6 Antibody [H00001238-B02P] - Analysis of negative control 293 cells (Black) and CCBP2 expressing 293 cells (Green) using CCBP2 purified mouse polyclonal antibody.

Product Discontinued

CC Chemokine Receptor D6 Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: CCBP2 (NP_001287.2, 1 a.a. - 384 a.a.) full-length human protein. MAATASPQPLATEDADSENSSFYYYDYLDEVAFMLCRKDAVVSFGKVFLPVFYSLIFVLGLSGNLLLLMVLLRYVPRRRMVEIYLLNLAISNLLFLVTLPFWGISVAWHWVFGSFLCKMVSTLYTINFYSGIFFISCMSLDKYLEIVHAQPYHRLRTRAKSLLLATIVWAVSLAVSIPDMVFVQTHENPKGVWNCHADFGGHGTIWKLFLRFQQNLLGFLLPLLAMIFFYSRIGCVLVRLRPAGQGRALKIAAALVVAFFVLWFPYNLTLFLHTLLDLQVFGNCEVSQHLDYALQVTESIAFLHCCFSPILYAFSSHRFRQYLKAFLAAVLGWHLAPGTAQASLSSCSESSILTAQEEMTGMNDLGERQSENYPNKEDVGNKSA
• Specificity: Reacts with chemokine binding protein 2.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: ACKR2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Western Blot
• Application Notes: This antibody is reactive against transfected lysate in WB, FACS and as a detection antibody in ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for CC Chemokine Receptor D6 Antibody

• ACKR2
• C-C chemokine receptor D6
• CCBP2
• CCR10CCR9D6CC-chemokine-binding receptor JAB61
• chemokine (C-C) receptor 9
• chemokine binding protein 2
• Chemokine receptor CCR-10
• Chemokine receptor CCR-9
• chemokine receptor D6
• chemokine-binding protein 2
• Chemokine-binding protein D6
• CMKBR9
• CMKBR9chemokine (C-C motif) receptor 9
• D6
• hD6
• MGC126678
• MGC138250

Background

This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ACKR2
• Entrez:
  • 1238(Human)
• Uniprot:
  • NP_001287.2(Human)