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Canine IL-10 DuoSet ELISA, 15 Plate



Product Details

Reactivity CaSpecies Glossary
Applications ELISA

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Canine IL-10 DuoSet ELISA, 15 Plate Summary

Assay Type
Solid Phase Sandwich ELISA
See PDF Datasheet for details
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details


Application Notes
No significant interference observed with available related molecules.
Read Publications using DY735.

Packaging, Storage & Formulations

Store the unopened product at 2 - 8 °C. Do not use past expiration date.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Canine IL-10 DuoSet ELISA, 15 Plate

  • CSIF
  • CSIFMGC126450
  • Cytokine synthesis inhibitory factor
  • IL10
  • IL-10
  • IL10A
  • IL-10MGC126451
  • interleukin 10
  • interleukin-10
  • TGIF


Interleukin-10 functions as an anti-inflammatory cytokine by inhibiting the expansion and activation of Th1 cells and Th17 cells and by promoting the development of M2 macrophages and regulatory T cells (Treg). Within a tumor microrenvironment, however, IL-10 can inhibit the expansion of both Treg and myeloid-derived suppressor cells (MDSC). IL-10 exerts protective effects including limiting tissue damage in arthritic inflammation and promoting muscle regeneration after injury, but it also contributes to the persistence of viral infections. IL-10 signals through a receptor complex composed of IL-10 R alpha and IL-10 R beta. IL-10 R beta additionally associates with IL-20 R alpha, IL-22 R alpha 1, or IL-28 R alpha to form the receptor complexes for IL-22, IL-26, IL-28, and IL-29.

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Publications for IL-10 (DY735)(14)

We have publications tested in 1 confirmed species: Canine.

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Showing Publications 1 - 10 of 14. Show All 14 Publications.
Publications using DY735 Applications Species
M Pelst, C Höbart, H de Rooster, B Devriendt, E Cox Immortalised canine buccal epithelial cells' CXCL8 secretion is affected by allergen extracts, Toll-like receptor ligands, IL-17A and calcitriol Veterinary research, 2022-09-13;53(1):72. 2022-09-13 [PMID: 36100942] (Canine) Canine
JP Bragato, GT Rebech, JH Freitas, MOD Santos, SF Costa, FR Eugênio, PSPD Santos, VMF de Lima miRNA-21 regulates CD69 and IL-10 expression in canine leishmaniasis PLoS ONE, 2022-03-24;17(3):e0265192. 2022-03-24 [PMID: 35324917] (Canine) Canine
JK Abbott, SK Chan, M MacBeth, JL Crooks, C Hancock, V Knight, EW Gelfand Fluctuations in quality of life and immune responses during intravenous immunoglobulin infusion cycles PLoS ONE, 2022-03-22;17(3):e0265852. 2022-03-22 [PMID: 35316278] (Canine) Canine
MT Verde, S Villanueva, A Loste, D Marteles, D Pereboom, T Conde, A Fernández Comparison of circulating CD4+, CD8+ lymphocytes and cytokine profiles between dogs with atopic dermatitis and healthy dogs Research in Veterinary Science, 2022-01-29;145(0):13-20. 2022-01-29 [PMID: 35134678] (Canine) Canine
PJ Alcolea, A Alonso, A Esteban, P Peris, A Cortés, JA Castillo, V Larraga IL12 p35 and p40 subunit genes administered as pPAL plasmid constructs do not improve protection of pPAL-LACK vaccine against canine leishmaniasis PLoS ONE, 2019-02-22;14(2):e0212136. 2019-02-22 [PMID: 30794597] (Canine) Canine
KL Oliveira S, V Marin Chik, G Luvizotto, AA Correa Lea, BF de Almeida, F De Rezende, PSP Dos Santos, G Fabrino Ma, VMF De Lima PD-1 and PD-L1 regulate cellular immunity in canine visceral leishmaniasis Comp. Immunol. Microbiol. Infect. Dis., 2018-12-14;62(0):76-87. 2018-12-14 [PMID: 30711051] (Canine) Canine
Suppression of Canine Dendritic Cell Activation/Maturation and Inflammatory Cytokine Release by Mesenchymal Stem Cells Occurs Via Multiple Distinct Biochemical Pathways Stem Cells Dev., 2016-12-22;0(0):. 2016-12-22 [PMID: 27842458] (Canine) Canine
Impact of LbSapSal Vaccine in Canine Immunological and Parasitological Features before and after Leishmania chagasi-Challenge PLoS ONE, 2016-08-24;11(8):e0161169. 2016-08-24 [PMID: 27556586] (Canine) Canine
JA MacDiarmid, V Langova, D Bailey, ST Pattison, SL Pattison, N Christense, LR Armstrong, VN Brahmbhatt, K Smolarczyk, MT Harrison, M Costa, NB Mugridge, I Sedliarou, NA Grimes, DL Kiss, B Stillman, CL Hann, GL Gallia, RM Graham, H Brahmbhatt Targeted Doxorubicin Delivery to Brain Tumors via Minicells: Proof of Principle Using Dogs with Spontaneously Occurring Tumors as a Model PLoS ONE, 2016-04-06;11(4):e0151832. 2016-04-06 [PMID: 27050167] (Canine) Canine
Shahbazi M, Zahedifard F, Taheri T, Taslimi Y, Jamshidi S, Shirian S, Mahdavi N, Hassankhani M, Daneshbod Y, Zarkesh-Esfahani S, Papadopoulou B, Rafati S Evaluation of Live Recombinant Nonpathogenic Leishmania tarentolae Expressing Cysteine Proteinase and A2 Genes as a Candidate Vaccine against Experimental Canine Visceral Leishmaniasis. PLoS ONE, 2015-07-21;10(7):e0132794. 2015-07-21 [PMID: 26197085] (Canine) Canine
Show All 14 Publications.

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By Victoria OsinskiUsing Flow Cytometry to Identify B Cell SubsetsIdentifying cellular subsets by flow cytometry requires careful and thorough planning in order to ensure the correct subset of cells are identified...  Read full blog post.

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Peroxisome proliferators are non-genotoxic carcinogens which are purported to exert their effect on cells by interacting with members of the nuclear hormone receptor superfamily known as peroxisome proliferator activated receptors (PPARs). There are f...  Read full blog post.

CD11b: Marker for a New Type of B Cell that Participates in Cell-Mediated Immunity
Think B lymphocytes just produce antibodies? Think again! Although, of course, B cells are vital for the humoral immune response, many studies in recent years have begun to uncover antibody-independent actions of B cells: regulating T cells and thus a...  Read full blog post.

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Gene Symbol IL10