CaMKIV Antibody


Western Blot: CaMKIV Antibody [NB120-3557] - Analysis of rat brain extract.

Product Details

Reactivity Hu, Mu, Rt, Ca, Pl, Pm, XpSpecies Glossary
Applications WB, IHC, IHC-Fr
1.0 mg/ml

Order Details

CaMKIV Antibody Summary

Synthetic Peptide: V(127)EKGYYSERDAADAVKQ(143)C.Immunizing peptide corresponds to amino acid residues 127-143 from mouse CaMKIV. This sequence is 94% conserved in rat and human CaMKIV.
Cytoplasmic and Nuclear
NB120-3557 detects CaM kinase IV (CaMKIV) from human, mouse, rat, canine, primate, arabidopsis and Xenopus Oocyte samples.
Immunogen affinity purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
0.05% Sodium Azide
1.0 mg/ml
Immunogen affinity purified


  • Western Blot 0.5 ug/ml
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1 ug/ml
Application Notes
Western Blot: use at a concentration of 0.5ug/ml. Immunohistochemistry: use at a concentration of 1ug/ml.Not tested in other applications.Optimal dilutions / concentrations should be determined by the end user.By Western blot, this antibody detects an ~55 kDa protein representing CaMKIV in HeLa cell lysate.

Reactivity Notes

Cross-reacts with Human, Rat, Mouse, Dog and Primate.Not yet tested in other species.

Alternate Names for CaMKIV Antibody

  • brain Ca(2+)-calmodulin-dependent protein kinase type IV
  • brain Ca++-calmodulin-dependent protein kinase type IV
  • calcium/calmodulin-dependent protein kinase IV
  • calcium/calmodulin-dependent protein kinase type IV catalytic chain
  • calcium/calmodulin-dependent protein kinase type IV
  • CAM kinase- GR
  • CAM kinase IV
  • CaM kinase-GR
  • CaMK IV
  • caMK
  • CaMK-GR
  • EC 2.7.11
  • EC
  • IV
  • MGC36771


CaM kinase IV (CaMKIV), in a calcium and calmodulin dependent manner, is implicated in phosphorylating numerous transcription factors including the CCAAT enhancer binding protein (C / EBP), serum response factor (SRF), and cyclic AMP response element binding protein (CBP). The nuclear localization of this protein is consistent with its role in mediating calcium-dependent gene expression. CaMKIV is particularly abundant in testis, T-cells, and neurons but is also found in other tissues to varying degrees. In neurons, CaMKIV is thought to play an important role in synaptic plasticity via its gene regulatory effects. In T-cells, this protein plays an important role in calcium signaling which could affect the transcription regulatory protein, nuclear factor of activated T-cells (NFAT). CaMKIV is encoded, along with calspermin, by the CaMKIV gene. It has been found that, in testes, CaMKIV is expressed in germ cells and found to be associated with chromatin. The association of CaMKIV with chromatin suggests a potential role in chromatin remodeling during nuclear condensation in spermatids.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol

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Positive Control Lysate(s)

Secondary Antibodies


Isotype Controls

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Contact Information

Product PDFs


Gene Symbol CAMK4

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