C1qR1/CD93 Antibody [Biotin]

• Reactivity: Hu
• Applications: WB, Flow
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Biotin
• Concentration: LYOPH

C1qR1/CD93 Antibody [Biotin] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human C1q R1/CD93
  Ala24-Lys580
  Accession # Q9NPY3
• Specificity: Detects human C1q R1/CD93 in Western blots. In Western blots, less than 5% cross-reactivity with recombinant mouse C1q R1 is observed.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: CD93
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 2.5 ug/10^6 cells
  • Western Blot 0.1 ug/mL
• Readout System:
  • Streptavidin Native Protein NBP2-29367
  • Streptavidin Native Protein NBP2-29370
  • Streptavidin Native Protein NBP2-29371

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for C1qR1/CD93 Antibody [Biotin]

• AA4 Antigen
• C1q R1
• C1q receptor 1
• C1q Rp
• C1q/MBL/SPA receptor
• C1qR(P)
• C1qR1
• C1qRp
• CD93 antigenC1qR
• CD93 molecule
• CD93
• CDw93C1QR1
• Collectin Receptor
• Complement component 1 q subcomponent receptor 1
• complement component 1, q subcomponent, receptor 1
• complement component C1q receptor
• dJ737E23.1
• ECSM3
• Ly68
• Matrix-remodeling-associated protein 4
• matrix-remodelling associated 4
• MXRA4

Background

C1q R1, also known as CD93, C1q R, and C1q RP, is a single chain glycoprotein expressed on cells of myeloid origin, endothelial cells, and hematopoietic progenitor cells. In vitro, this molecule may mediate the enhancement of phagocytosis upon interaction with soluble defense collagens (1, 2).

1. Kim, T.S. et al. (2000) Mol. Immunol. 37:377.
2. Dean, Y.D. and P. Gasque (2001) Eur. J. Immunol. 31:1370.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for C1qR1/CD93 Antibody (BAF2379)(1)

Publication using BAF2379

• Malarstig A, Silveira A, Wagsater D, Ohrvik J, Backlund A, Samnegard A, Khademi M, Hellenius ML, Leander K, Olsson T, Uhlen M, de Faire U, Eriksson P, Hamsten A Plasma CD93 concentration is a potential novel biomarker for coronary artery disease. J. Intern. Med., 2011-03-21;270(0):229-36. 2011-03-21 [PMID: 21332844] (ELISA Development, Human)

Bioinformatics

• Gene Symbol: CD93
• Uniprot:
  • Q9NPY3()