C-Peptide Antibody (790904) [Alexa Fluor® 350]

• Reactivity: Hu
• Applications: IHC, ICC/IF
• Clone: 790904
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 350

C-Peptide Antibody (790904) [Alexa Fluor® 350] Summary

• Immunogen: Human C-Peptide synthetic peptide
  EAEDLQVGQVELGGGPGAGSLQPLALEGSLQ
  Accession # P01308
• Specificity: Detects human C-Peptide in direct ELISAs.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for C-Peptide Antibody (790904) [Alexa Fluor® 350]

• C-P
• C-Peptide
• IDDM2
• ILPR
• Insulin C-Peptide
• insulin
• IRDN
• MODY10
• Proinsulin C-Peptide
• proinsulin

Background

Insulin is a peptide hormone that facilitates the cellular uptake of glucose by regulating the appearance of membrane glucose transporters. The single chain insulin propeptide consists of a 30 amino acid B chain (aa 25-54), a C-Peptide (aa 55-89), and a 21 aa A chain (aa 90-110). Removal of the C-Peptide by proteolysis enables the formation of mature Insulin, a disulfide-linked heterodimer of the A and B chains. Circulating C-peptide levels are elevated in hyperinsulinism, obesity, and type II diabetes. The human C-Peptide shares 61% and 68% aa sequence identity with mouse and rat C-Peptide, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.