C-Peptide Antibody (2B7)

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Product Details

Summary
Reactivity Hu, Bv(-), Mu(-), Po(-), Rt(-)Species Glossary
Applications ELISA, RI, RIA
Clone
2B7
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

C-Peptide Antibody (2B7) Summary

Immunogen
Recombinant full length protein.
Epitope
The three-dimensional structure generated by N- and C- terminal regions of C-peptide separated by beta-turn at position 47-50 of proinsulin.
Localization
Secreted
Specificity
Affinity (Kd) > 1 x 10^8.Binds to the human free C-peptide and proinsulin molecules.No cross reactivity with human, bovine, porcine insulins.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
INS
Purity
Protein A purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Radioimmunoassay 1:100-1:2000
  • Radioimmunodiffusion
Application Notes
Competitive ELISA or RIA detection of C-peptide in human serum without or after immunospecific removal of proinsulin (with solid-phased ab8299 (1D6) to human proinsulin)Construction of a sensitive two-site sandwich EIA/ RIA immunosorbent assays for the measurement of total (including proinsulin convertion intermediates) human proinsulin in serum. ab8297 used in conjunction with this antibody would be suitable.Specific immunosorbtional (with solid-phase 2B7) removal of total proinsulin and C-peptide molecules from serum samples before the measurement of human insulin

Reactivity Notes

Cross-reacts with Human. Does not react with Bovine, Mouse, Rat or Pig

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.4)
Preservative
0.09% Sodium Azide
Purity
Protein A purified

Alternate Names for C-Peptide Antibody (2B7)

  • C-P
  • C-Peptide
  • IDDM2
  • ILPR
  • Insulin C-Peptide
  • insulin
  • IRDN
  • MODY10
  • Proinsulin C-Peptide
  • proinsulin

Background

This antibody detects human Insulin and a different epitope than the monoclonal, ab8297.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol INS
Entrez