BRIP1/FANCJ Antibody

ELISA: BRIP1/FANCJ Antibody [22070002]

Product Discontinued

BRIP1/FANCJ Antibody Summary

• Immunogen: This antibody is specific for the N Terminus Region of the target protein.
• Specificity: This product is specific for Human BRIP1.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: BRIP1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Western Blot 1:5000-1:20000
• Application Notes: This antibody is useful in ELISA and Western Blot.

Reactivity Notes

Human.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

Manufactured by SDIX's proprietary Genomic Antibody Technology™. GAT FAQs.

Alternate Names for BRIP1/FANCJ Antibody

• ATP-dependent RNA helicase BRIP1
• BACH1
• BACH1BRCA1/BRCA2-associated helicase 1
• BRCA1 interacting protein C-terminal helicase 1
• BRCA1-associated C-terminal helicase 1
• BRCA1-binding helicase-like protein BACH1
• BRCA1-interacting protein 1
• BRCA1-interacting protein C-terminal helicase 1
• BRIP1
• EC 3.6.1
• EC 3.6.4.13
• FACJ
• FANCJ
• FANCJFanconi anemia group J protein
• FLJ90232
• MGC126521
• MGC126523
• OF
• Protein FACJ

Background

BRIP1 (also called BACH1) is a helicase that interacts with the BRCT domain of BRCA1 and has a role in BRCA1-dependent DNA repair and checkpoint. BRIP1 has recently been found to be defective in Fanconi anemia complementation group J. BRIP1/FANCJ has a function in the Fanconi anemia pathway that is independent of BRCA1 and downstream of FANCD2 activation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for BRIP1/FANCJ Antibody (22070002)(2)

Publications using 22070002

• Garrison C, Lastwika K, Zhang Y et al. Proteomic Analysis, Immune Dysregulation, and Pathway Interconnections With Obesity J Proteome Res. 2017-01-06 [PMID: 27769113] (MiAr)
  
  Details:
  Analysis is performed on plasma proteomic data to identify how obesity can alter pathways and to highlight the risk factor for disease in subjects with a high body mass index.
• Rho JH, Lampe PD. High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays J Proteome Res. 2013-05-03 [PMID: 23541305] (MiAr)
  
  Details:
  A novel method using antibody microarrays is used to detect autoantibody-antigen complexes that can potentially be useful for detection and characterization of diseases.

Bioinformatics

• Gene Symbol: BRIP1
• Uniprot:
  • NM_032043(Human)