Western Blot: PALB2 Antibody [NB100-60440] - Detection of Human PALB2 by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa and cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit ...read more
Immunohistochemistry: PALB2 Antibody [NB100-60440] - Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti- PALB2 used at a dilution of 1:1,000 (1 ug/ml). Detection: DAB
Western Blot: PALB2 Antibody [NB100-60440] - Detection of Human PALB2 on HeLa whole cell lysate using NB100-60440. PALB2 was also immunoprecipitated by rabbit anti-PALB2 antibody NB100-60439.
PALB2 (partner and localizer of BRCA2) interacts with BRCA2 and promotes BRCA2 localization and stability. PALB2 is also known as FANCN. Bi-allelic mutations in PALB2 result in Fanconi anemia disorder and breast cancer susceptibility. At the cellular level, PALB2 is important to the DNA damage response and chromosome stability and is essential to BRCA2 function.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
The recent relationship of BRCA1 and 53BP1 The p53-binding protein 1 (53BP1) is a DNA damage response factor, which is recruited to nuclear structures at the site of DNA damage. DNA double-strand breaks (DSBs) are mutations that are detrimental to cell viability and genome stability, and m... Read full blog post.
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