BCMA/TNFRSF17 Antibody

Images

 
Western Blot: BCMA Antibody [NB100-94350] - Western blot analysis of BCMA in human spleen (A) tissue lysate, K562 (B), and U937 (C) cell lysates with anti-BCMA at 5 ìg/ml.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB100-94350
    • Availability
      Product Discontinued

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BCMA/TNFRSF17 Antibody Summary

Immunogen
Rabbit anti-BCMA polyclonal antibody was raised against a synthetic peptide mapping at the carboxy terminus of human BCMA (8).
Specificity
BCMA
Clonality
Polyclonal
Host
Rabbit
Gene
TNFRSF17
Purity
IgG purified
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Applications/Dilutions

Dilutions
  • Western Blot 2-5 ug/ml
Application Notes
This polyclonal antibody can be used for detection of BCMA by Western blot at 2 to 5 ug/ml.
Positive Control
BCMA/TNFRSF17 Lysate (NBL1-17151)

Reactivity Notes

This antibody is reactive against Human

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS
Preservative
0.02% Sodium Azide
Purity
IgG purified

Alternate Names for BCMA/TNFRSF17 Antibody

  • B cell maturation antigen
  • B-cell maturation protein
  • BCMA
  • BCMAtumor necrosis factor receptor superfamily member 17
  • BCMB-cell maturation factor
  • CD269 antigen
  • CD269
  • TNFRSF17
  • tumor necrosis factor receptor superfamily, member 17

Background

Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 (1-4) and April/TALL-2, respectively, (3,5). BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion (1,2). April regulates immunological and non-immunological cell growth. Three receptors, BCMA (for B cell maturation protein), TACI, and BAFF-R, for BAFF were recently identified (6,7). BCMA, like TACI, binds BAFF and April. BAFF and its receptors induce B cell development and survival, activate NF-kappaB and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for BCMA/TNFRSF17 Antibody (NB100-94350)

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Diseases for BCMA/TNFRSF17 Antibody (NB100-94350)

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Bioinformatics

Gene Symbol TNFRSF17
Entrez