BCL11B Antibody - BSA Free

Immunohistochemistry-Paraffin: BCL11B Antibody [NBP2-33549] - Analysis in human skin and pancreas tissues. Corresponding RNA-seq data are presented for the same tissues.

Immunocytochemistry/Immunofluorescence: BCL11B Antibody [NBP2-33549] - Staining of human cell line MCF7 shows localization to nucleus & nucleoli fibrillar center. Antibody staining is shown in green.

Immunohistochemistry-Paraffin: BCL11B Antibody [NBP2-33549] - Staining of human cerebral cortex shows weak to moderate nuclear positivity in neurons.

Immunohistochemistry: BCL11B Antibody [NBP2-33549] - Staining of mouse basal forebrain shows nuclear positivity in neurons of caudate putamen.

Immunohistochemistry: BCL11B Antibody [NBP2-33549] - Staining of mouse nucleus accumbens shows nuclear positivity in neurons.

Immunohistochemistry: BCL11B Antibody [NBP2-33549] - Staining of mouse parietal association cortex shows nuclear immunoreactivity in neurons.

Immunohistochemistry-Paraffin: BCL11B Antibody [NBP2-33549] - Staining of human lymph node shows strong nuclear positivity in subsets of non-germinal center cells.

Immunohistochemistry: BCL11B Antibody [NBP2-33549] - Staining of mouse brain shows moderate to strong positivity in more than 75 % of neurons in the olfactory bulb.

Immunohistochemistry-Paraffin: BCL11B Antibody [NBP2-33549] - Staining of human pancreas shows no nuclear positivity in exocrine glandular cells as expected.

Immunohistochemistry-Paraffin: BCL11B Antibody [NBP2-33549] - Staining of human skin shows moderate to strong nuclear positivity in epidermal cells.

• Reactivity: Hu, Mu, Rt
• Applications: ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

BCL11B Antibody - BSA Free Summary

• Immunogen: This antibody was developed against a recombinant protein corresponding to amino acids: QGNPQHLSQRELITPEADHVEAAILEEDEGLEIEEPSGLGLMVGGPDPDLLTCG
• Predicted Species: Rat (98%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: BCL11B
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.
• Control Peptide:

  BCL11B Protein (NBP2-33549PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for BCL11B Antibody - BSA Free

• B-cell CLL/lymphoma 11B (zinc finger protein)
• B-cell CLL/lymphoma 11B
• B-cell CLL/lymphoma 11B/T-cell receptor delta constant region fusion protein
• B-cell lymphoma/leukaemia 11B
• B-cell lymphoma/leukemia 11B
• BCL-11B
• BCL11B/TRDC fusion
• COUP-TF-interacting protein 2
• CTIP-2
• CTIP2ZNF856B
• hRit1
• hRIT1-alpha
• Radiation-induced tumor suppressor gene 1 protein
• RIT1
• zinc finger protein hRit1 alpha

Background

The BCL11B gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. The specific function of this gene has not yet been determined. Two alternatively spliced transcript

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for BCL11B Antibody (NBP2-33549)(1)

Publication using NBP2-33549

• Wang CY, Sun YT, Fang KM, Ho CH. Function of B-Cell CLL/Lymphoma 11B in Glial Progenitor Proliferation and Oligodendrocyte Maturation. Front Mol Neurosci. 2018-01-24 [PMID: 29416501] (ICC/IF, Mouse)

Bioinformatics

• Gene Symbol: BCL11B
• Uniprot:
  • Q9C0K0(Human)