Bcl-xL Antibody

Western Blot: Bcl-Xl Antibody [NB100-56312] - Western blot analysis for Bcl-XL using this antibody at 2 ug/ml against 20 ug of Rh30 cell lysate.

Product Discontinued

Bcl-xL Antibody Summary

• Immunogen: A synthetic peptide corresponding to amino acids 3-14 that is common in human and mouse Bcl-XL and Bcl-XS protein was used as immunogen.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: BCL2L1
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1-2 ug/ml
• Control:

  Bcl-xL Overexpression Lysate

Reactivity Notes

Predicted to cross react with Mouse.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Protein G purified

Alternate Names for Bcl-xL Antibody

• Apoptosis regulator Bcl-X
• bcl2-L-1
• BCL2-like 1
• bcl-2-like protein 1
• BCLXBCL2LBcl-X
• BclxL
• Bcl-xL
• BCL-XL/S
• BCLXS
• bcl-xS
• DKFZp781P2092

Background

The Bcl-2 family consists of anti-apoptotic (or cell survival) genes, such as Bcl-2, Bcl-XL and pro-apoptotic (or cell death) genes including Bax and BAD. The balance of expression between these genes may determine the death or survival of a cell. In addition to its anti-apoptotic effect, Bcl-X has two isoforms, resulting from alternative splicing. Bcl-XL (long) is a 241 amino acid protein (27 kD) and Bcl-XS is a 178 amino acid protein with predicted molecular weight of 19.5 kD.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: BCL2L1
• Entrez:
  • 598(Human)
• Uniprot:
  • NP_612815(Human)