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Bcl-xL Products

Antibodies
Bcl-xL Antibody - BSA Free
Bcl-xL Antibody - BSA Free
NB100-56104
Species: Hu, Mu, Rt, Ca, Bv, Ma, Sh
Applications: WB, IHC, IP
Host: Rabbit Polyclonal
Formulation Catalog # Availability Price  
Bcl-xL Antibody (2052A) [Unco ...
Bcl-xL Antibody (2052A) [Unconjuga...
MAB894
HAF008). A specific band was detected for Bcl-xLat approximately 25 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Western Blot Bcl-xL Antibody (2052A) [Unconjugated]
VC003). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using VisUCyte Antigen Retrieval Reagent-Basic (Catalog # VCTS021). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to secretetory vesicles in epithelial cells. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents." class="big_lightbox" target="_blank"> Immunohistochemistry Bcl-xL Antibody (2052A) [Unconjugated]
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC
Host: Rabbit Monoclonal
Bcl-xL Antibody (7B2.5) - Azi ...
Bcl-xL Antibody (7B2.5) - Azide an...
NBP1-28559
Species: Hu, Mu, Rt, RM
Applications: WB, Flow, IP
Host: Mouse Monoclonal
Conjugate Catalog # Availability Size Price
ELISA Kits
Human/Mouse Total Bcl-xL DuoS ...
Human/Mouse Total Bcl-xL DuoSet IC...
DYC894-2
Species: Hu, Mu
Applications: ELISA
Conjugate Catalog # Availability Size Price
Rat Bcl-xL ELISA Kit (Colorim ...
Rat Bcl-xL ELISA Kit (Colorimetric)
NBP2-77043
Species: Rt
Applications: ELISA
Lysates
Bcl-xL Overexpression Lysate
Bcl-xL Overexpression Lysate
NBP2-08227
Species: Hu
Applications: WB
Bcl-xL Overexpression Lysate
Bcl-xL Overexpression Lysate
NBL1-07946
Species: Hu
Applications: WB
Proteins
Recombinant Human Bcl-xL Prot ...
Recombinant Human Bcl-xL Protein
NBP2-34899
Species: Hu
Applications: PAGE
Recombinant Human Bcl-xL (min ...
Recombinant Human Bcl-xL (minus C-...
894-BX
Species: Hu
Applications: Inhibition Activity
Formulation Catalog # Availability Price  
Recombinant Mouse Bcl-xL (min ...
Recombinant Mouse Bcl-xL (minus C-...
878-BC
Species: Mu
Applications: Inhibition Activity
Formulation Catalog # Availability Price  

Description

Bcl-x, a member of the Bcl-2 protein family, inhibits cell death, or apoptosis (1). Bcl-x is expressed as two isomeric forms, Bcl-xL and Bcl-xS, and is typically present in the cytosol in association with the mitochondrial membrane. Bcl-xL forms heterodimers with various proteins, including Bax, Bak and Bcl-2 (2). It has been found that eterodimerization with Bax does not seem to be required for anti-apoptotic activity (3). Since Bcl-xL can form an ion channel in synthetic lipid membranes, there is a strong possibility that this property plays a role in heterodimerization-independent cell survival (4). The Bcl-X(S) isoform promotes apoptosis.

Bioinformatics

Entrez Mouse
Rat
Human
Uniprot Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 598
Alternate Names
  • Apoptosis regulator Bcl-X
  • Bcl2-L-1
  • bcl2-L-1
  • BCL2-like 1
  • bcl-2-like protein 1
  • BCLXBCL2LBcl-X
  • BCLXL
  • bcl-xL
  • BCL-XL/S
  • BCLXS
  • bcl-xS
  • DKFZp781P2092

Research Areas for Bcl-xL

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Phospho-Specific
Tumor Suppressors

Related Bcl-xL Blog Posts

Check out the latest blog posts on Bcl-xL.
BAG3 - Hsp70 is my friend!
The BAG proteins are a large family of chaperone regulators governing a wide range of cell processes such as proliferation, survival, stress response, tumorigenesis, neuronal differentiation, growth arrest and apoptosis as reviewed in Takayama et al1....    Read more.
Read more Bcl-xL related blogs.