Bcl-10 Antibody - BSA Free

Western Blot: Bcl10 Antibody [NB500-215] - WB detection of Bcl10 in transfected 293 cells with NB500-215 antibody at a dilution of 1:500

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

Bcl-10 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit Bcl-10 Antibody - BSA Free (NB500-215) is a polyclonal antibody validated for use in WB. Anti-Bcl-10 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: C-terminal sequence of human Bcl-10.
• Specificity: Reacts with the C terminal sequence [EMFLPLRSRTVSRQC] of Bcl10.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: BCL10
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500 -1:1000
• Application Notes: Western blot - Use at 1:500 to 1:1,000 dilution. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry.
  
  The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
• Theoretical MW: 26 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human. Other species have not been tested.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Bcl-10 Antibody - BSA Free

• B-cell CLL/lymphoma 10CIPERCLAPB-cell lymphoma/leukemia 10
• Bcl10
• Bcl-10
• CARD-containing apoptotic signaling protein
• CARD-containing molecule enhancing NF-kappa-B
• CARD-containing proapoptotic protein
• CARD-like apoptotic protein
• CARMEN
• caspase-recruiting domain-containing protein
• cCARMEN
• c-E10
• c-E10bcl-10
• CED-3/ICH-1 prodomain homologous E10-like regulator
• Cellular homolog of vCARMEN
• cellular-E10
• CIPER
• CLAP
• hCLAP
• Mammalian CARD-containing adapter molecule E10
• mE10
• mE10CARD containing molecule enhancing NF-kB

Background

Bcl10 is a novel gene with an amino-terminal caspase-recruiting domain (CARD), which is thought to be involved in mucosa-associated lymphoid tissue lymphomas and in the pathogenesis of several other human malignancies.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Bcl-10 Antibody (NB500-215)(1)

Publication using NB500-215

• Nagy ZS, Rui H, Stepkowski SM et al. A preferential role for STAT5, not constitutively active STAT3, in promoting survival of a human lymphoid tumor. J Immunol. 2006-10-15 [PMID: 17015686]

Bioinformatics

• Gene Symbol: BCL10
• Entrez:
  • 8915(Human)