Bcl-10 Antibody [mFluor Violet 500 SE]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: mFluor Violet 500 SE

Bcl-10 Antibody [mFluor Violet 500 SE] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: C-terminal sequence of human Bcl-10.
• Specificity: Reacts with the C terminal sequence [EMFLPLRSRTVSRQC] of Bcl10.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: BCL10
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NB500-215. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Reactivity Notes

Human. Other species have not been tested.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Bcl-10 Antibody [mFluor Violet 500 SE]

• B-cell CLL/lymphoma 10CIPERCLAPB-cell lymphoma/leukemia 10
• Bcl10
• Bcl-10
• CARD-containing apoptotic signaling protein
• CARD-containing molecule enhancing NF-kappa-B
• CARD-containing proapoptotic protein
• CARD-like apoptotic protein
• CARMEN
• caspase-recruiting domain-containing protein
• cCARMEN
• c-E10
• c-E10bcl-10
• CED-3/ICH-1 prodomain homologous E10-like regulator
• Cellular homolog of vCARMEN
• cellular-E10
• CIPER
• CLAP
• hCLAP
• Mammalian CARD-containing adapter molecule E10
• mE10
• mE10CARD containing molecule enhancing NF-kB

Background

Bcl-10 is an adaptor protein with a caspase recruitment domain (CARD) that promotes apoptosis and activates pro-caspase 9 and NF-kB (1-2). Bcl-10 also interacts with other CARD domain containing proteins including CARD9, 10, 11 and 14. Bcl-10 is found to form a complex with MALT1, a protein known to be translocated in MALT lymphomas. Bcl-10 and MALT1 play a critical role in antigen receptor

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: BCL10