Bag-1 Antibody (RM356)

Images

 
Western Blot: Bag-1 Antibody (RM356) [NBP2-77438] - Western Blot of HeLa cell lysate using NBP2-77438.
Immunohistochemistry: Bag-1 Antibody (RM356) [NBP2-77438] - Immunohistochemical staining of formalin fixed and paraffin embedded human breast cancer tissue sections using NBP2-77438.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
RM356
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Bag-1 Antibody (RM356) Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
A peptide corresponding to human BAG-1 (Bcl-2-associated athanogene 1)
Specificity
This antibody reacts to total human BAG-1 protein, including long (BAG-1L), medium (BAG-1M) and short (BAG-1S) isoforms
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
BAG1
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:500-1:1000
  • Western Blot 1:1000 - 1:2000

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
50% Glycerol/PBS with 1% BSA
Preservative
0.09% Sodium Azide
Purity
Protein A purified

Alternate Names for Bag-1 Antibody (RM356)

  • BAG family molecular chaperone regulator 1
  • Bag1
  • Bag-1
  • Bcl-2 associating athanogene-1 protein
  • Bcl-2-associated athanogene 1
  • BCL2-associated athanogene
  • Bcl-2-binding protein
  • glucocortoid receptor-associated protein RAP46,46-KD
  • HAP
  • RAP46

Background

The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. At least three protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) start site, and alternative, downstream, AUG translation initiation sites.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Blogs on Bag-1.

BAG3 - Hsp70 is my friend!
The BAG proteins are a large family of chaperone regulators governing a wide range of cell processes such as proliferation, survival, stress response, tumorigenesis, neuronal differentiation, growth arrest and apoptosis as reviewed in Takayama et al1....  Read full blog post.

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Bioinformatics

Gene Symbol BAG1