B220/CD45R Antibody (YKIX753.22.2)

Images

 
Flow Cytometry: B220/CD45R Antibody (YKIX753.22.2) [NB100-65018] - Figure A. RPE conjugated Rat anti Canine CD45R and Alexa Fluor 488 conjugated Rat IgG1 isotype control. Figure B. RPE conjugated Mouse anti Canine CD45R ...read more
Flow Cytometry: B220/CD45R Antibody (YKIX753.22.2) [NB100-65018] - Figure A. Alexa Fluor 488 conjugated Rat anti Dog CD44 and Alexa Fluor 647 conjugated Rat IgG2b isotype control. Figure B. Alexa Fluor 488 conjugated ...read more
Flow Cytometry: B220/CD45R Antibody (YKIX753.22.2) [NB100-65018] - Figure A. Alexa Fluor 488 conjugated Rat anti Canine CD44 and RPE conjugated Rat IgG2a isotype control. Figure B. Alexa Fluor 488 conjugated Rat anti ...read more

Product Details

Summary
Reactivity CaSpecies Glossary
Applications Flow, IHC, IHC-Fr, IP
Clone
YKIX753.22.2
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

B220/CD45R Antibody (YKIX753.22.2) Summary

Immunogen
Canine thymocytes
Specificity
This antibody recognizes canine CD45R and was clustered as a canine CD45R at the first canine Leucocyte Antigen workshop. It precipitates an antigen of 220kD from Con A Blasts (1) and may be against a CD45R isoform. It is expressed on subsets of leucocytes (neutrophils are weak) in canine blood of all out bred mongrels and beagles tested.
Isotype
IgG2b
Clonality
Monoclonal
Host
Rat
Gene
PTPRC
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1:50-1:100
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunoprecipitation 1:10-1:500

Reactivity Notes

Reacts with Canine.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Phosphate buffered saline
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein G purified

Alternate Names for B220/CD45R Antibody (YKIX753.22.2)

  • B220
  • CD45 antigen
  • CD45R
  • EC 3.1.3.48
  • L-CA
  • LY5
  • protein tyrosine phosphatase, receptor type, C
  • receptor-type tyrosine-protein phosphatase C
  • T200 glycoprotein
  • T200 leukocyte common antigen
  • T200receptor type, c polypeptide

Background

CD45 is a family of single chain transmembraneous glycoproteins consisting of at least four isoforms (220, 205, 190, 180 kDa) which share a common large intracellular domain. Their extracellular domains are heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1. CD45 is expressed on cells of the human hematopoietic lineage (including hematopoietic stem cells) with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions. Antibodies recognizing a common epitope on all of the isoforms are termed CD45 whilst those recognizing only individual isoforms are termed CD45RA or CD45RO etc.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NB100-64358
Species: Hu
Applications: Flow, IHC, IHC-P
NB100-524
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, Flow-IC
NBP1-19371
Species: Hu, Mu, Rt, Ca, Rb
Applications: WB, Simple Western, Flow, ICC/IF, IHC, IHC-Fr, IHC-P
NB600-1071
Species: Mu, Rt
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP
NBP1-49045
Species: Mu, Rt
Applications: Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, Cell Depl, CyTOF-ready, InhibTFunc
NBP1-43435
Species: Hu, Mu
Applications: WB, Flow
NBP1-85599
Species: Hu
Applications: WB, IHC, IHC-P
NB110-89474
Species: Hu, Mu, Rt, Bv
Applications: WB, Simple Western, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, ISH, Single Cell Western
NBP1-47386
Species: Hu, Mu, Rb(-)
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P, Flow-IC
7270-IL/CF
Species: Hu
NBP2-25196
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, In vitro, CyTOF-ready
NBP1-88968
Species: Hu
Applications: WB, IHC, IHC-P
NBP2-36561
Species: Hu, Mu
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-Fr, IP, B/N
NB100-65018
Species: Ca
Applications: Flow, IHC, IHC-Fr, IP

Publications for B220/CD45R Antibody (NB100-65018) (0)

There are no publications for B220/CD45R Antibody (NB100-65018).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for B220/CD45R Antibody (NB100-65018) (0)

There are no reviews for B220/CD45R Antibody (NB100-65018). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for B220/CD45R Antibody (NB100-65018) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 405 Labeled NB100-65018AF405
Alexa Fluor 488 Labeled NB100-65018AF488
Alexa Fluor 647 Labeled NB100-65018AF647
Alexa Fluor 700 Labeled NB100-65018AF700
Allophycocyanin Labeled NB100-65018APC
DyLight 350 Labeled NB100-65018UV
DyLight 405 Labeled NB100-65018V
DyLight 488 Labeled NB100-65018G
DyLight 680 Labeled NB100-65018FR
DyLight 755 Labeled NB100-65018IR
PE Labeled NB100-65018PE
PerCP Labeled NB100-65018PCP

Additional B220/CD45R Products

Array NB100-65018

Bioinformatics Tool for B220/CD45R Antibody (NB100-65018)

Discover related pathways, diseases and genes to B220/CD45R Antibody (NB100-65018). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for B220/CD45R Antibody (NB100-65018)

Discover more about diseases related to B220/CD45R Antibody (NB100-65018).
 

Pathways for B220/CD45R Antibody (NB100-65018)

View related products by pathway.

PTMs for B220/CD45R Antibody (NB100-65018)

Learn more about PTMs related to B220/CD45R Antibody (NB100-65018).
 

Research Areas for B220/CD45R Antibody (NB100-65018)

Find related products by research area.

Blogs on B220/CD45R

There are no specific blogs for B220/CD45R, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our B220/CD45R Antibody (YKIX753.22.2) and receive a gift card or discount.

Bioinformatics

Gene Symbol PTPRC