Species: Hu
Applications: WB, Flow, ICC/IF, IHC
Host: Rabbit Monoclonal
Species: Hu
Applications: Flow, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: Flow, ICC/IF, IHC
Host: Mouse Monoclonal
Description
CD45R/B220, a member of the protein tyrosine phosphate family and a major cell surface glycoprotein, represents a restricted form of the CD45 family which primarily recognizes only cells of B-lineage from pro-B cell through mature B lymphocytes and, prior to the availability of anti-CD19 MAbs, was commonly used as a pan B-cell marker. (1-5) It also reacts with certain activated T cells, as well as non-MHC-restricted lytically active lymphokine-activated killer (LAK) cells. (1, 6) In vivo administration of RA3-6B2 has been shown to affect differentiation of both T and B cells in normal mice and reduce the level of anti-DNA antibodies and lymphadenopathies in MRL/lpr mice. (7, 8)
Bioinformatics
| Product By Gene ID |
5788 |
| Alternate Names |
- B220
- CD45 antigen
- CD45R
- EC 3.1.3.48
- L-CA
- LY5
- protein tyrosine phosphatase, receptor type, C
- receptor-type tyrosine-protein phosphatase C
- T200 glycoprotein
- T200 leukocyte common antigen
- T200receptor type, c polypeptide
|
