Artemin Antibody (RM0074-6G32) - Azide and BSA Free

• Reactivity: Mu
• Applications: WB, IHC
• Clone: RM0074-6G32
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: LYOPH

Artemin Antibody (RM0074-6G32) - Azide and BSA Free Summary

• Description: Novus Biologicals Rat Artemin Antibody (RM0074-6G32) - Azide and BSA Free (NBP1-21701) is a monoclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Mouse recombinant Artemin
• Isotype: IgG2
• Clonality: Monoclonal
• Host: Rat
• Gene: ARTN
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:50-1:200
  • Western Blot 1:500-1:1000

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein A or G purified
• Reconstitution Instructions: Reconstitute with sterilized PBS to a final concentration of 0.5 mg/ml.

Alternate Names for Artemin Antibody (RM0074-6G32) - Azide and BSA Free

• Artemin
• ARTN
• Enovin
• EVN
• EVNneurotrophic factor
• NBN
• Neublastin

Background

The protein encoded by this gene is a member of the glial cell line-derived neurotophic factor (GDNF) family of ligands, a group of ligands within the TGF-beta superfamily of signalling molecules. GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenrative disease. Artemin has been shown in culture to support the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. Its role in the PNS and CNS is further substantiated by its expression pattern in the proximity of these neurons. This protein is a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor. Four alternatively spliced transcripts have been described, two of which encode the same protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ARTN
• Entrez:
  • 9048(Human)
  • 11876(Mouse)