Artemin Products

Description

The protein encoded by this gene is a member of the glial cell line-derived neurotophic factor (GDNF) family of ligands which are a group of ligands within the TGF-beta superfamily of signaling molecules. GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenerative disease. Artemin has been shown in culture to support the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. Its role in the PNS and CNS is further substantiated by its expression pattern in the proximity of these neurons. This protein is a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Bioinformatics

Product By Gene ID	9048
Alternate Names	Artemin ARTN Enovin EVN EVNneurotrophic factor NBN Neublastin

Research Areas for Artemin

Find related products by research area and learn more about each of the different research areas below.

Cancer
Growth and Development
Neuronal Cell Markers
Neuroscience