Arginase 1/ARG1/liver Arginase Antibody (ARG1/1125) [Janelia Fluor® 646]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC, IHC-P, ICC/IF
Clone
ARG1/1125
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 646

Order Details

Arginase 1/ARG1/liver Arginase Antibody (ARG1/1125) [Janelia Fluor® 646] Summary

Immunogen
Recombinant fragment (87 Amino acid residues around aa 1-150) of human ARG1 protein
Localization
Cytoplasmic
Marker
Hepatocellular Carcinoma Marker
Specificity
Recognizes a protein of 35-38kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.
Isotype
IgG3 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
ARG1
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunofluorescence
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus

Alternate Names for Arginase 1/ARG1/liver Arginase Antibody (ARG1/1125) [Janelia Fluor® 646]

  • AI
  • ARG1
  • Arginase 1
  • arginase, liver
  • Arginase-1
  • EC 3.5.3.1
  • Liver Arginase
  • Liver-type arginase
  • PGIF
  • Type I Arginase

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-47998AF350
Alexa Fluor 405 NBP2-47998AF405
Alexa Fluor 488 NBP2-47998AF488
Alexa Fluor 532 NBP2-47998AF532
Alexa Fluor 594 NBP2-47998AF594
Alexa Fluor 647 NBP2-47998AF647
Alexa Fluor 700 NBP2-47998AF700
Alexa Fluor 750 NBP2-47998AF750
Allophycocyanin NBP2-47998APC
Biotin NBP2-47998B
DyLight 350 NBP2-47998UV
DyLight 405 NBP2-47998V
DyLight 488 NBP2-47998G
DyLight 550 NBP2-47998R
DyLight 594 NBP2-47998DL594
DyLight 650 NBP2-47998C
DyLight 680 NBP2-47998FR
DyLight 755 NBP2-47998IR
FITC NBP2-47998F
HRP NBP2-47998H
Janelia Fluor 549 NBP2-47998JF549
Janelia Fluor 646 NBP2-47998JF646
PE NBP2-47998PE
PerCP NBP2-47998PCP

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Bioinformatics

Gene Symbol ARG1