RELM beta Antibody - BSA Free

Western Blot: RELM beta Antibody [NB200-204] - WB detection of secreted mouse RELM-beta from the media of transfected HEK 293T cells with NB200-204 antibody at a dilution of 1:500.

• Reactivity: Mu
• Applications: WB, Flow, ICC/IF, IHC, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

RELM beta Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit RELM beta Antibody - BSA Free (NB200-204) is a polyclonal antibody validated for use in IHC, WB, Flow, ICC/IF and IP. Anti-RELM beta Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Reacts with the residues 32-46 of the mouse RELM beta protein
• Specificity: Reacts with the residues 32-46 of the mouse RELM beta protein.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: RETNLB
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1:10-1:1000
  • Immunocytochemistry/ Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunoprecipitation 1:10-1:500
  • Western Blot 1:500 -1:1000
• Application Notes: Western blot - Use at 1:500 to 1:1,000 dilution. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry-Frozen and Paraffin.

Reactivity Notes

Mouse

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for RELM beta Antibody - BSA Free

• C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich proteinprecursor 2
• CCRG
• Colon and small intestine-specific cysteine-rich protein
• Colon carcinoma-related gene protein
• cysteine-rich secreted A12-alpha-like protein 1
• Cysteine-rich secreted protein A12-alpha-like 1
• Cysteine-rich secreted protein FIZZ2
• FIZZ1
• FIZZ2RELM-beta
• found in inflammatory zone 1
• HXCP2XCP2
• RELM beta
• RELMb
• RELMbeta
• resistin like beta
• resistin-like beta
• RETNL2

Background

A family of resistin-like molecules (RELMs) has been identified in rodents and humans. Resistin is a hormone produced by fat cells. RELM alpha is a secreted protein that has a restricted tissue distribution with highest levels in adipose tissue. Another family member, RELM beta, is a secreted protein expressed only in the gastrointestinal tract, particularly the colon, in both mouse and human. RELM beta gene expression is highest in proliferative epithelial cells and is markedly increased in tumors, suggesting a role in intestinal proliferation. Resistin and the RELMs share a cysteine composition and other signature features. Thus, the RELMs together with resistin comprise a class of tissue-specific signaling molecules.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for RELM beta Antibody (NB200-204)(2)

Publications using NB200-204

• Ding R, Xie H, Sang S et al. Astragaloside IV alleviates hypoxic pulmonary hypertension by inhibiting RELM-beta to reduce PINK1/Parkin-mediated mitophagy in pulmonary artery smooth muscle cells (PASMCs). British journal of pharmacology 2025-08-13 [PMID: 40801101]
• Tukler Henriksson J, Coursey TG, Corry DB et al. IL-13 Stimulates Proliferation and Expression of Mucin and Immunomodulatory Genes in Cultured Conjunctival Goblet Cells. Invest Ophthalmol Vis Sci 2015-07-01 [PMID: 26132778] (Mouse)

Bioinformatics

• Gene Symbol: RETNLB
• Entrez:
  • 57262(Mouse)