Orthogonal Strategies: Western Blot: Apolipoprotein L1 Antibody [NBP1-89033] - Analysis in human cell lines A-431 and MCF-7 using anti-APOL1 antibody. Corresponding APOL1 RNA-seq data are presented for the same ...read more
Immunocytochemistry/ Immunofluorescence: Apolipoprotein L1 Antibody [NBP1-89033] - Staining of vascular BM whole mounts with antibodies to proteins detected in the proteome analysis. The same treatment of vascular BM ...read more
Immunohistochemistry-Paraffin: Apolipoprotein L1 Antibody [NBP1-89033] - Staining of human tonsil shows no positivity in non-germinal center cells as expected.
Immunohistochemistry-Paraffin: Apolipoprotein L1 Antibody [NBP1-89033] - Staining of human colon shows positivity in plasma.
Immunohistochemistry-Paraffin: Apolipoprotein L1 Antibody [NBP1-89033] - Staining of human skin shows positivity in plasma.
Simple Western: Apolipoprotein L1 Antibody [NBP1-89033] - Simple Western lane view shows a specific band for APOL1 in 0.2 mg/ml of RT-4 (left) and U-251MG sp (right) lysate. This experiment was performed under ...read more
Simple Western: Apolipoprotein L1 Antibody [NBP1-89033] - Electropherogram image(s) of corresponding Simple Western lane view. Apolipoprotein L1 antibody was used at 1:30 dilution on RT-4 and U-251MG sp lysates(s).
This antibody was developed against Recombinant Protein corresponding to amino acids: SNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASASRPRVTEPISAESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLVYESKHLHEGAKSETAEELKKVAQELEEKLNILNN
Immunogen affinity purified
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Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.2) and 40% Glycerol
0.02% Sodium Azide
Immunogen affinity purified
Alternate Names for Apolipoprotein L1 Antibody
apolipoprotein L, 1
Apolipoproteins are protein components of plasma lipoproteins. The apolipoprotein L gene family encodes six highly homologous proteins designated apoL-I to -VI, which are associated with large high density type lipoproteins (HDL). The human apoL family maps to chromosome 22q12.1- 13.1 within a 127,000-bp region . apoL has been characterized as a pancreas specific, 383-amino acid, 42 kDa protein that contains a 12-amino acid secretory signal peptide. The apoL genes have TATA-less promoters and contain putative sterol regulatory elements, suggesting that transcription of these genes may be coordinated with that of the low density lipoprotein receptor and genes in pathways involving the synthesis of triglycerides and cholesterol. apoL homologs can undergo 10 fold changes in expression during atherosclerotic changes in vascular endothelial cells, which includes the inflammatory reaction of atherosclerotic lesions.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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