Androgen R/NR3C4 Antibody (SPM335) - IHC-Prediluted

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Product Details

Summary
Reactivity Hu, Mu(-)Species Glossary
Applications IHC, IHC-P
Clone
SPM335
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
IHC-Prediluted

Order Details

Androgen R/NR3C4 Antibody (SPM335) - IHC-Prediluted Summary

Immunogen
A synthetic peptide, aa 299-315, (STEDTAEYSPFKGGYTK) of human AR.
Localization
Nuclear
Marker
Marker of Androgen Dependence
Specificity
Recognizes a protein of 110kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin.This MAb is superb for staining of formalin/paraffin tissues.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
AR
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Hu-chromosome location: Xq12 Immunohistochemistry-Paraffin 0.5 - 1 ug/ml for 30 minutes at RT; Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10 - 20 min followed by cooling at RT for 20 minutes. The 7mL size is a pre-diluted size and no additional dilutions are required before using this item for the intended application.
Theoretical MW
110 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C.
Buffer
10 mM PBS with 0.05% BSA
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

The prediluted antibody does not require any mixing, dilution, reconstitution, or titration; the antibody is ready-to-use and optimized for staining.

Alternate Names for Androgen R/NR3C4 Antibody (SPM335) - IHC-Prediluted

  • AIS
  • Androgen R
  • androgen receptor
  • AndrogenR
  • AR
  • DHTR
  • DHTRTFM
  • Dihydrotestosterone receptorHYSP1
  • HUMARA
  • NR3C4
  • NR3C4KD
  • Nuclear receptor subfamily 3 group C member 4
  • SBMA
  • SMAX1
  • SMAX1SBMA
  • spinal and bulbar muscular atrophy

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-47855AF350
Alexa Fluor 405 NBP2-47855AF405
Alexa Fluor 488 NBP2-47855AF488
Alexa Fluor 532 NBP2-47855AF532
Alexa Fluor 594 NBP2-47855AF594
Alexa Fluor 647 NBP2-47855AF647
Alexa Fluor 700 NBP2-47855AF700
Alexa Fluor 750 NBP2-47855AF750
Allophycocyanin NBP2-47855APC
Biotin NBP2-47855B
DyLight 350 NBP2-47855UV
DyLight 405 NBP2-47855V
DyLight 488 NBP2-47855G
DyLight 550 NBP2-47855R
DyLight 594 NBP2-47855DL594
DyLight 650 NBP2-47855C
DyLight 680 NBP2-47855FR
DyLight 755 NBP2-47855IR
FITC NBP2-47855F
HRP NBP2-47855H
Janelia Fluor 549 NBP2-47855JF549
Janelia Fluor 646 NBP2-47855JF646
PE NBP2-47855PE
PerCP NBP2-47855PCP

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Bioinformatics

Gene Symbol AR