Reactivity | Hu, Mu(-)Species Glossary |
Applications | Flow, IHC, IHC-P, CyTOF-ready, ICC/IF |
Clone | AR441 |
Clonality | Monoclonal |
Host | Mouse |
Conjugate | Unconjugated |
Format | Azide and BSA Free |
Concentration | 1.0 mg/ml |
Immunogen | A synthetic peptide, aa 299-315, (STEDTAEYSPFKGGYTK) of human AR. |
Localization | Nuclear |
Marker | Marker of Androgen Dependence |
Specificity | Recognizes a protein of 110kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin.This MAb is superb for staining of formalin/paraffin tissues. |
Isotype | IgG1 Kappa |
Clonality | Monoclonal |
Host | Mouse |
Gene | AR |
Purity | Protein A or G purified |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
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Application Notes | Hu-chromosome location: Xq12 Immunohistochemistry-Paraffin 0.5 - 1 ug/ml for 30 minutes at RT; Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10 - 20 min followed by cooling at RT for 20 minutes. |
Theoretical MW | 110 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Storage | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer | 10 mM PBS |
Preservative | No Preservative |
Concentration | 1.0 mg/ml |
Purity | Protein A or G purified |
Secondary Antibodies |
Isotype Controls |
Alexa Fluor 350 | NBP2-47854AF350 | |
Alexa Fluor 405 | NBP2-47854AF405 | |
Alexa Fluor 488 | NBP2-47854AF488 | |
Alexa Fluor 532 | NBP2-47854AF532 | |
Alexa Fluor 594 | NBP2-47854AF594 | |
Alexa Fluor 647 | NBP2-47854AF647 | |
Alexa Fluor 700 | NBP2-47854AF700 | |
Alexa Fluor 750 | NBP2-47854AF750 | |
Allophycocyanin | NBP2-47854APC | |
Biotin | NBP2-47854B | |
DyLight 350 | NBP2-47854UV | |
DyLight 405 | NBP2-47854V | |
DyLight 488 | NBP2-47854G | |
DyLight 550 | NBP2-47854R | |
DyLight 594 | NBP2-47854DL594 | |
DyLight 650 | NBP2-47854C | |
DyLight 680 | NBP2-47854FR | |
DyLight 755 | NBP2-47854IR | |
FITC | NBP2-47854F | |
HRP | NBP2-47854H | |
Janelia Fluor 549 | NBP2-47854JF549 | |
Janelia Fluor 646 | NBP2-47854JF646 | |
PE | NBP2-47854PE | |
PerCP | NBP2-47854PCP |
Diseases for Androgen R/NR3C4 Antibody (NBP2-47854)Discover more about diseases related to Androgen R/NR3C4 Antibody (NBP2-47854).
| Pathways for Androgen R/NR3C4 Antibody (NBP2-47854)View related products by pathway.
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Gene Symbol | AR |