Aminopeptidase N/CD13 Antibody (APN/514) [DyLight 405]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC, IHC-P
Clone
APN/514
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 405

Order Details

Aminopeptidase N/CD13 Antibody (APN/514) [DyLight 405] Summary

Immunogen
Recombinant human CD13 protein
Localization
Cell Surface
Marker
Myeloid Cell Marker
Specificity
This MAb recognizes an extracellular epitope of an integral membrane glycoprotein of 150kDa, identified as CD13. This antigen is present on most cells of myeloid origin including granulocytes, monocytes, mast cells, and GM-progenitor cells. It is also expressed by the majority of AML, CML in myeloid blast crisis, and in a smaller fraction of lymphoid leukemias. It is absent from normal lymphocytes, platelets and erythrocytes. CD13 is also present on fibroblasts; endothelial cells, epithelial cells from renal proximal tubules and intestinal brush border, bone marrow stromal cells, osteoclasts, and cells lining bile duct canaliculi. CD13 is identical to aminopeptidase N (APN), a prominent membrane-bound metalloprotease present on the surface of intestinal brush border and renal tubules. CD13 plays a role in metabolism of biologically active peptides, in phagocytosis, and in bactericidal/tumoricidal activities. It also serves as a receptor for human coronaviruses (HCV). The lineage-restricted pattern of expression of CD13 within the hemopoietic compartment suggests that it may be important in myeloid cell differentiation.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
ANPEP
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Aminopeptidase N/CD13 Antibody (APN/514) [DyLight 405]

  • alanyl (membrane) aminopeptidase
  • Alanyl aminopeptidase
  • Aminopeptidase M
  • Aminopeptidase N
  • ANPEP
  • AP-M
  • APN
  • AP-N
  • CD13 antigen
  • CD13
  • CD13APN
  • EC 3.4.11
  • EC 3.4.11.2
  • gp150
  • LAP1
  • Microsomal aminopeptidase
  • Myeloid plasma membrane glycoprotein CD13
  • p150
  • PEPN
  • PEPNhAPN

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-47892AF350
Alexa Fluor 405 NBP2-47892AF405
Alexa Fluor 488 NBP2-47892AF488
Alexa Fluor 532 NBP2-47892AF532
Alexa Fluor 594 NBP2-47892AF594
Alexa Fluor 647 NBP2-47892AF647
Alexa Fluor 700 NBP2-47892AF700
Alexa Fluor 750 NBP2-47892AF750
Allophycocyanin NBP2-47892APC
Allophycocyanin/Cy7 NBP2-47892APCCY7
Biotin NBP2-47892B
DyLight 350 NBP2-47892UV
DyLight 405 NBP2-47892V
DyLight 488 NBP2-47892G
DyLight 550 NBP2-47892R
DyLight 594 NBP2-47892DL594
DyLight 650 NBP2-47892C
DyLight 680 NBP2-47892FR
DyLight 755 NBP2-47892IR
FITC NBP2-47892F
HRP NBP2-47892H
Janelia Fluor 549 NBP2-47892JF549
Janelia Fluor 646 NBP2-47892JF646
PE NBP2-47892PE
PE/Atto594 NBP2-47892PEATT594
PE/Cy5.5 NBP2-47892PECY55
PE/Cy7 NBP2-47892PECY7
PerCP NBP2-47892PCP

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Bioinformatics Tool for Aminopeptidase N/CD13 Antibody (NBP2-47892V)

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Diseases for Aminopeptidase N/CD13 Antibody (NBP2-47892V)

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Bioinformatics

Gene Symbol ANPEP