Aminopeptidase N/CD13 Products

Description

Alanine aminopeptidase (CD13) is expressed on the majority of peripheral blood monocytes and granulocytes. CD13 is also expressed by the majority of acute myeloid leukemias, chronic myeloid leukemias in myeloid blast crisis, a smaller percentage of lymphoid leukemias and myeloid cell lines. CD13 is also found in several types of non hematopoietic cells such as fibroblasts and endothelial cells and in a soluble form in blood plasma. CD13 is not expressed on B cells, T cells, platelets or erythrocytes. In the mouse, CD13 is a non-covalently linked homodimer of approximately 150kD subunits expressed by a variety of cells including monocytes, macrophages, dendritic cell and veiled cells. CD13 plays a role in biologically active peptide metabolism, in the control of growth and differentiation, in phagocytosis and in bactericidal/tumoricidal activities. CD13 also serves as a receptor for human coronaviruses.

CD13 is commonly used as a biomarker to detect damage to the kidneys, and that may be used to help diagnose certain kidney disorders. Therefore, CD13 antibodies are useful tools for cancer and renal disorder research.

Bioinformatics

Entrez	16790 Mouse 290 Human 81641 Rat
Uniprot	AAH58928 Human AAH58928.1 Human P15144 Human P97449 Mouse
Product By Gene ID	290
Alternate Names	alanyl (membrane) aminopeptidase Alanyl aminopeptidase Aminopeptidase M aminopeptidase N AP-M AP-N CD13 antigen CD13APN EC 3.4.11 EC 3.4.11.2 gp150 GP150 LAP1 Microsomal aminopeptidase Myeloid plasma membrane glycoprotein CD13 P150 p150 PEPNhAPN

Diseases related to Aminopeptidase N/CD13

Discover more about diseases related to Aminopeptidase N/CD13.

Malignant Neoplasms
Neoplasms
Hypertensive Disease
Tumor Angiogenesis
Adenocarcinoma
Severe Acute Respiratory Syndrome
Prostatic Neoplasms
Cell Invasion
Malignant Neoplasm Of Prostate
Neoplasm Metastasis
Meningeal Disorder
Viral Meningitis
Neoplasm Invasiveness
Fetal Growth Retardation
Carcinoma
Fibrosarcoma
Fibrosis
Esophageal Neoplasms
Coronavirus Infections
Mental Disorders

Pathways for Aminopeptidase N/CD13

View related products by pathway and learn more about each of the pathways below.

Localization
Angiogenesis
Reverse Transcription
Coagulation
Translation
Immune Response
Pathogenesis
Cholesterol Homeostasis
Inflammatory Response

Research Areas for Aminopeptidase N/CD13

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Cellular Markers
Hematopoietic Stem Cell Markers
Immunology
Mesenchymal Stem Cell Markers
Stem Cell Markers

Bioinformatics Tool for Aminopeptidase N/CD13

Discover related pathways, diseases and genes to Aminopeptidase N/CD13. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.