ALDH18A1 Antibody - BSA Free

Immunoprecipitation:ALDH18A1 AntibodyNBP3-30292] -Detection of human ALDH18A1/P5CS by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from 293T cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-ALDH18A1/P5CS antibody NBP3-30292 (lot NBP3-30292-1) used for IP at 6 µg per reaction. ALDH18A1/P5CS was also immunoprecipitated by rabbit anti-ALDH18A1/P5CS.. For blotting immunoprecipitated ALDH18A1/P5CS, NBP3-30292 was used at 0.4 µg/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.

• Reactivity: Hu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

ALDH18A1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit ALDH18A1 Antibody - BSA Free (NBP3-30292) is a polyclonal antibody validated for use in WB and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Between 745 and 795
• Assay Type: [Assay Type]
• Sample Volume: [Sample Volume]
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ALDH18A1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Tris-citrate/phosphate pH 7 -8.
• Preservative: 0.09% Sodium Azide
• Purity: Affinity purified

Alternate Names for ALDH18A1 Antibody - BSA Free

• aldehyde dehydrogenase 18 family, member A1
• Aldehyde dehydrogenase family 18 member A1
• delta-1-pyrroline-5-carboxylate synthase
• EC 2.1.2.11
• EC 2.3.3.13
• GSASdelta1-pyrroline-5-carboxlate synthetase
• MGC117316
• P5CSdelta-1-pyrroline-5-carboxylate synthetase
• PYCSEC 1.2.1.41
• pyrroline-5-carboxylate synthetase (glutamate gamma-semialdehyde synthetase)

Background

ALDH18A1, or Delta-1-pyrroline-5-carboxylate synthase, contains a long 88 kDa and a short 87 kDa isoform, and is involved in the catalytic conversion of glutamate to glutamate 5-semialdehyde. Current research on ALDH18A1 is being conducted to determine the relation between the protein and a variety of diseases and disorders, including neurodegeneration, pneumonia, connective tissue disease, mental retardation, hypoornithinemia, tuberculosis, microcephaly, Alzheimer's disease, gastroesophageal reflux disease, and dementia. The protein has been linked to biosynthesis and metabolic pathways where it interacts with PUS1, UQCRFS1, ICT1, OAT, and MYC.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ALDH18A1