AG-2 Antibody


Immunohistochemistry-Paraffin: AG-2 Antibody [NB110-17780] - Immunohistochemical staining with NB110-17780, anti- AG-2 antibody, in formalin-fixed, paraffin-embedded normal colon tissue at 1:100 dilution.

Product Details

Reactivity Hu, BovineSpecies Glossary
Applications IHC, IHC-P
1.0 mg/ml

AG-2 Antibody Summary

A synthetic peptide corresponding to an internal region of human AGR2 (within residues 50-100). [UniProt# O95994]
Predicted Species
Bovine (94%). Backed by our 100% Guarantee.
Immunogen affinity purified
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Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS and 30% Glycerol
0.05% Sodium Azide
1.0 mg/ml
Immunogen affinity purified


  • Immunohistochemistry 1:100
  • Immunohistochemistry-Paraffin 1:100
Application Notes
This AGR2 antibody is useful for ELISA and Immunohistochemistry paraffin embedded sections.
Read Publications using
NB110-17780 in the following applications:

  • IHC
    2 publications
  • WB
    1 publication

Reactivity Notes

Human. Immunogen sequence has 94% homology to bovine and 88% homology to mouse.

Alternate Names for AG-2 Antibody

  • AG2
  • AG-2
  • AG2member 17
  • AGR2
  • anterior gradient 2 homolog (Xenopus laevis)
  • anterior gradient homolog 2 (Xenopus laevis)
  • GOB-4
  • hAG-2
  • HPC8
  • PDIA17
  • secreted cement gland homolog


Originally discovered in Xenopus laevis wherein it plays a role during early neural development, AGR2 (anterior gradient protein 2 homolog) is now known as a member of protein disulfide isomerase (PDI) family of ER-resident proteins which is expressed in a variety of normal as well as transformed epithelial tissues. AGR2 has been implicated in the folding of proteins as a chaperone protein. It interacts with LYPD3, DAG1 (alphaDAG1) and MUC2 (disulfide-linked), and is essential for MUC2 translation as well as secretion. AGR2 plays a key role in the production of mucus by intestinal cells and has also been suggested to be a proto-oncogene that may involve in cellular migration, differentiation and growth. Differential expression of AGR2 was first found in estrogen receptor (ER)-positive breast cancer cell lines and subsequently, elevated AGR2 levels have been seen in subsets of other cancers also wherein its upregulation enhances classical hallmarks of cancer such as metastasis, invasion, colony formation, and proliferation.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for AG-2 Antibody (NB110-17780)(5)

Reviews for AG-2 Antibody (NB110-17780) (0)

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Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor 405 Labeled NB110-17780AF405
Alexa Fluor 488 Labeled NB110-17780AF488
Alexa Fluor 647 Labeled NB110-17780AF647
Alexa Fluor 700 Labeled NB110-17780AF700
Biotin Labeled NB110-17780B
DyLight 405 Labeled NB110-17780V
DyLight 488 Labeled NB110-17780G
DyLight 550 Labeled NB110-17780R
DyLight 650 Labeled NB110-17780C
FITC Labeled NB110-17780F

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Blogs on AG-2

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Contact Information

Product PDFs


Gene Symbol AGR2

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