ADE2 Antibody (4F4)

Western Blot: ADE2 Antibody (4F4) [H00010606-M01] - PAICS monoclonal antibody (M01), clone 4F4. Analysis of PAICS expression in human placenta.

Sandwich ELISA: ADE2 Antibody (4F4) [H00010606-M01] - Detection limit for recombinant GST tagged PAICS is 1 ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA
• Clone: 4F4
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

ADE2 Antibody (4F4) Summary

• Immunogen: PAICS (AAH10273, 1 a.a. ~ 426 a.a) full length recombinant protein with GST tag.MATAEVLNIGKKLYEGKTKEVYELLDSPGKVLLQSKDQITAGNAARKNHLEGKAAISNKITSCIFQLLQEAGIKTAFTRKCGETAFIAPQCEMIPIEWVCRRIATGSFLKRNPGVKEGYKFYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIFEILEKSWLPQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGDRSQQKDKQSYRDLKEVTPEGLQMVKKNFEWVAER
• Specificity: PAICS (4F4)
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: PAICS
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • Western Blot
  • ELISA
• Application Notes: Antibody reactive against recombinant protein on ELISA.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for ADE2 Antibody (4F4)

• ADE2
• AIR carboxylase
• AIRCADE2H1
• DKFZp781N1372
• MGC1343
• MGC5024
• multifunctional protein ADE2
• PAIS
• phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazolesuccinocarboxamide synthetase
• SAICAR synthetase

Background

This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PAICS
• Entrez:
  • 10606(Human)
• OMIM:
  • 172439(Human)
• Uniprot:
  • AAH10273(Human)