ACSL1 Antibody - BSA Free

Immunohistochemistry-Paraffin: ACSL1 Antibody [NBP2-99339] - Immunochemical staining of human ACSL1 in human kidney with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.

Immunohistochemistry-Paraffin: ACSL1 Antibody [NBP2-99339] - Immunochemical staining of human ACSL1 in human hepatoma with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

ACSL1 Antibody - BSA Free Summary

• Description: This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.
• Immunogen: Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human ACSL1.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ACSL1
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin 1:200-1:1000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.03% Proclin 300
• Purity: Antigen and protein A Affinity-purified

Alternate Names for ACSL1 Antibody - BSA Free

• ACS1LACS 2
• Acyl-CoA synthetase 1
• acyl-CoA synthetase long-chain family member 1
• EC 6.2.1
• FACL1EC 6.2.1.3
• fatty-acid-Coenzyme A ligase, long-chain 1
• LACS 1
• LACSlong-chain 2
• lignoceroyl-CoA synthase
• Long-chain acyl-CoA synthetase 1
• Long-chain acyl-CoA synthetase 2
• Long-chain fatty acid-CoA ligase 2
• long-chain fatty-acid-coenzyme A ligase 1
• long-chain-fatty-acid--CoA ligase 1
• Palmitoyl-CoA ligase 1
• Palmitoyl-CoA ligase 2
• paltimoyl-CoA ligase 1

Background

Long-chain-fatty-acid--CoA ligase 1, or ACSL1, is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. These proteins play an important role in lipid biosynthesis and fatty acid degradation. Like other isozymes of this family, ALCS1 converts free long-chain fatty acids into fatty acyl-CoA esters. ACSL1 preferentially uses palmitoleate, oleate and linoleate, and altered expression of ACSL1 is thought to increase accumulation of triglycerides in the liver.

ALCS1 is strongly expressed in the heart, kindey, liver, skeletal muscle, and erythroid cells, and to a lesser extent in lung, brain, placenta and pancreas. This protein is predominantly expressed during the early stages of erythroid development, and expression is weak in reticulocytes and young erythrocytes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ACSL1