Aconitase 1 Assay Kit (Colorimetric)

Aconitase 1 Assay Kit (Colorimetric) [KA0876] - The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.

Product Discontinued

Aconitase 1 Assay Kit (Colorimetric) Summary

• Description: Quality control test: Standard curve Aconitase Assay Kit is used for measuring aconitase activity.
• Assay Type: Colorimetric
• Sample Volume: 2-50 uL
• Kit Type: Assay Kit (Colorimetric)
• Gene: ACO1

Applications/Dilutions

• Dilutions:
  • Functional

Packaging, Storage & Formulations

• Storage: Store at 4°C.

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Aconitase 1 Assay Kit (Colorimetric)

• aconitase 1, soluble
• Aconitase
• aconitate hydratase
• Citrate hydro-lyase
• cytoplasmic aconitate hydratase
• EC 4.2.1
• EC 4.2.1.3
• Ferritin repressor protein
• IREB1IREBP1
• IRE-BP 1
• IREBP
• Iron regulatory protein 1
• iron-responsive element binding protein 1
• Iron-responsive element-binding protein 1
• IRP1ACONS

Background

Aconitase 1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs). IREs are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. The iron-induced binding to the IRE results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA. Thus, IREB1 plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Kits are guaranteed for 6 months from date of receipt.

Publications for Aconitase 1 Kit (KA0876)(2)

Publications using KA0876

• Kadam PD, Chuan HH. Erratum to: Rectocutaneous fistula with transmigration of the suture: a rare delayed complication of vault fixation with the sacrospinous ligament. Int Urogynecol J. 2016-03-01 [PMID: 26811110]
  
  Details:
  This citation used the HRP version of this antibody.
• Li X, Liu Y, Yang Y et al. High levels of malic acid production by the bioconversion of corn straw hydrolyte using an isolated Rhizopus delemar strain. Biotechnology and Bioprocess Engineering 2014-04-22 (Func, Fungi)

Bioinformatics

• Gene Symbol: ACO1