ACK1 Antibody [Janelia Fluor® 669]

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Janelia Fluor 669

ACK1 Antibody [Janelia Fluor® 669] Summary

• Immunogen: Produced in rabbits immunized with E. coli-derived Human ACK1 fragment.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TNK2
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen and protein A Affinity-purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for ACK1 Antibody [Janelia Fluor® 669]

• ACK1
• ACK-1
• ACK1ACKp21cdc42Hs
• activated CDC42 kinase 1
• activated Cdc42-associated kinase 1
• activated p21cdc42Hs kinase
• EC 2.7.10
• EC 2.7.10.2
• FLJ44758
• FLJ45547
• TNK2
• Tyrosine kinase non-receptor protein 2
• tyrosine kinase, non-receptor, 2

Background

The ACK1 gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-termi

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TNK2