ABL2 Antibody - BSA Free

Western Blot: ABL2 Antibody [NBP1-18875] - Whole cell lysate from HeLa cells. ARG was also immunoprecipitated by rabbit anti-ARG antibodies NBP1-18876 and NBP1-18877.

• Reactivity: Hu, Mu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

ABL2 Antibody - BSA Free Summary

• Immunogen: The immunogen recognized by this antibody maps to a region between residue 750 and 800 of human Abelson-related gene protein using the numbering given in entry NP_009298.1 (GeneID 27).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ABL2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 2-5 ug/mg lysate
  • Western Blot 1:2000-1:10000
• Theoretical MW: 128 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Use in Mouse reported in scientific literature (PMID:23099479).

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Tris-Citrate/Phosphate (pH 7.0 - 8.0)
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for ABL2 Antibody - BSA Free

• Abelson murine leukemia viral (v-abl) oncogene homolog 2
• Abelson murine leukemia viral oncogene homolog 2
• Abelson-related gene protein
• Abelson-relatedgene)
• ABL2
• ABLL
• arg tyrosine kinase
• ARG
• EC 2.7.10
• EC 2.7.10.2
• FLJ22224
• FLJ31718
• FLJ41441
• tyrosine-protein kinase ABL2
• Tyrosine-protein kinase ARG
• v-abl Abelson murine leukemia viral oncogene homolog 2

Background

This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinase. The protein is highly similar to the ABL1 protein, including the tyrosine kinase, SH2 and SH3 domains, and has a role in cytoskeletal rearrangements by its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ETV6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ABL2 Antibody (NBP1-18875)(4)

Publications using NBP1-18875

• Amado-Azevedo J, van Stalborch AD, Valent ET et al. Depletion of Arg/Abl2 improves endothelial cell adhesion and prevents vascular leak during inflammation Angiogenesis 2021-03-26 [PMID: 33770321] (Human)
• Li Xian, Cai Yuqi, Goines Jillian et al. Ponatinib Combined With Rapamycin Causes Regression of Murine Venous Malformation. Sci Rep. 2019-03-01 [PMID: 30626204] (IP, WB, Human)
• Aman J, van Bezu J et al. Effective treatment of edema and endothelial barrier dysfunction with imatinib. Circulation 2012-04-12 [PMID: 23099479] (WB, Mouse)
• Syros G, Maysky M. High-pressure loculated pericardial effusion in postpericardiotomy syndrome. Circulation 2012-05-29 [PMID: 22644372] (Human)

Bioinformatics

• Gene Symbol: ABL2
• Entrez:
  • 27(Human)
• Uniprot:
  • P42684(Human)