ABCE1 Antibody (SR2116) - BSA Free

Western Blot: ABCE1 Antibody (SR2116) [NBP3-22133] - Western blot analysis using NBP3-22133 in HeLa cell lysate.

• Reactivity: Hu, Mu, Rt
• Applications: WB, Flow, ICC/IF, IHC, IP
• Clone: SR2116
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

ABCE1 Antibody (SR2116) - BSA Free Summary

• Description: Novus Biologicals Rabbit ABCE1 Antibody (SR2116) - BSA Free (NBP3-22133) is a recombinant monoclonal antibody validated for use in IHC, WB, Flow, ICC/IF and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthesized peptide derived from human ABCE1 (Uniprot #: P61221)
• Specificity: Detects endogenous levels of total ABCE1
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: ABCE1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1:20-1:100
  • Immunocytochemistry/ Immunofluorescence 1:50-1:200
  • Immunohistochemistry 1:100-1:200
  • Immunoprecipitation 1:50
  • Western Blot 1:1000-1:2000
• Theoretical MW: 67 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 10mM PBS (pH 7.4), 150mM sodium chloride, 0.05% BSA, 50% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for ABCE1 Antibody (SR2116) - BSA Free

• 2'-5'-oligoadenylate-binding protein
• ATP-binding cassette, sub-family E (OABP), member 1
• huHP68
• OABP
• Ribonuclease 4 inhibitor
• ribonuclease L (2'-5'-oligoisoadenylate synthetase-dependent) inhibitor
• RLIABC38
• RNase L inhibitor
• RNASEL1
• RNASELIRNS4IATP-binding cassette sub-family E member 1

Background

ATP-binding cassette sub-family E member 1 (ABCE1) is a member of the ATP-binding cassette sub-family E, but is not a membrane transporter.

ABCE-1 interacts with RNASEL to inhibit its endoribonuclease activity, and antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. ABCE1 is activated by encephalomyocarditis virus (EMCV) and HIV-1, and recently it has been found to be essential for the assembly of immature immunodeficiency virus capsids.

ABCE1 antibodies are useful tools for HIV studies and research on the ATP-binding cassette families.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ABCE1