ABCB11 Antibody (HL2803)

ABCB11 antibody [HL2803] detects ABCB11 protein by immunohistochemical analysis.Sample: Paraffin-embedded human tissue.ABCB11 stained by ABCB11 antibody [HL2803] (NBP3-48735) diluted at 1:100.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Boiled and unboiled mouse liver extracts (50 ug) were separated by 5% SDS-PAGE, and the membrane was blotted with ABCB11 antibody [HL2803] (NBP3-48735) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

ABCB11 antibody [HL2803] detects ABCB11 protein by immunohistochemical analysis.Sample: Paraffin-embedded mouse liver.ABCB11 stained by ABCB11 antibody [HL2803] (NBP3-48735) diluted at 1:100.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

• Reactivity: Hu, Mu
• Applications: WB, IHC
• Clone: HL2803
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated

ABCB11 Antibody (HL2803) Summary

• Description: Novus Biologicals Rabbit ABCB11 Antibody (HL2803) (NBP3-48735) is a recombinant monoclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: Recombinant protein encompassing a sequence within the Intracellular domain of human ABCB11. The exact sequence is proprietary.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: ABCB11
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot 1:500-1:3000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein A purified

Alternate Names for ABCB11 Antibody (HL2803)

• ABC member 16, MDR/TAP subfamily
• ABC16
• ATP-binding cassette sub-family B member 11
• ATP-binding cassette, sub-family B (MDR/TAP), member 11
• bile salt export pump
• BSEP
• BSEPPFIC2
• EC 3.6.3
• EC 3.6.3.44
• PFIC-2
• PGY4
• progressive familial intrahepatic cholestasis 2
• sister p-glycoprotein
• SPGPBRIC2

Background

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ABCB11