2B4/CD244/SLAMF4 Antibody (244F4) Summary
The immunogen for this antibody is CD244.
Protein A or G purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
Aqueous buffer, may contain carrier protein/stabilizer (proprietary).
0.09% Sodium Azide
Protein A or G purified
- Western Blot 1:100-1:2000
- Flow Cytometry 1:10-1:1000
This 244F4 antibody has been tested by flow cytometric analysis of IL-2-stimulated mouse splenocytes. This can be used at less than or equal to 0.06 ug per test. A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 uL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. This 244F4 antibody has also been reported for use in immunoblotting (WB). It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
Alternate Names for 2B4/CD244/SLAMF4 Antibody (244F4)
- CD244 antigen
- CD244 molecule, natural killer cell receptor 2B4
- NAILNK cell activation-inducing ligand
- natural killer cell receptor 2B4
- NKR2B4NK cell type I receptor protein 2B4,2B4CD244 natural killer cell receptor 2B4
- SLAMF4NK cell activation inducing ligand NAIL
Mouse CD244, also known as 2B4, is a receptor belonging to the CD2 family of proteins involved in non-MHC dependent cytotoxicity. Expression is found on natural killer (NK) cells and many NKT cells and CD8+ cells. In C57BL/6 mice, two splice variants exist that differ in the length of the cytoplasmic domain. The long form functions in an inhibitory manner through signaling through SHP-2, while the short form functions in an activating manner. The ligand for CD244 is CD48 which is expressed on all hematopoietic cells. Recent data suggests that CD244 interactions with CD48, but not CD2 interaction with CD48, is essential for IL-2-driven expansion and activation of murine NK cells. Reports show CD244 expression can discriminate hematopoietic progenitors. Hematopoietic stem cells (HSC) are highly purified as CD150+CD244-CD48- cells while non-self-renewing multipotent hematopoietic progenitors (MPP) are CD244+CD150-CD48- and the most restricted progenitors are CD48+CD244+CD150-.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
Customers Who Viewed This Item Also Viewed...
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P, IP
Applications: WB, ICC/IF, IHC, IHC-P
Applications: WB, ELISA, S-ELISA
Applications: Flow, ELISA(Cap), ELISA(Det), ELISA(Sta)
Applications: WB, Flow, CostimT, Neut
Species: Hu, Mu
Applications: WB, Simple Western
Applications: WB, Flow, AgAct, ICC
Applications: WB, B/N, Flow, IHC, IHC-Fr
Species: Mu, Rt
Applications: Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, Cell Depl, InhibTFunc
Applications: WB, Flow
Applications: Flow, Block
Publications for 2B4/CD244/SLAMF4 Antibody (NBP2-00223) (0)
There are no publications for 2B4/CD244/SLAMF4 Antibody (NBP2-00223).
By submitting your publication information earn gift cards and discounts for future purchases.
Reviews for 2B4/CD244/SLAMF4 Antibody (NBP2-00223) (0)
There are no reviews for 2B4/CD244/SLAMF4 Antibody (NBP2-00223).
By submitting a review earn points towards our Rewards Program.
- 250 points for product review
- 500 additional points for an image with your product review
- Double points (500) if you are the first to review this product
- Double points (1000) if you are the first to review this product with an image
Product General Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
FAQs for 2B4/CD244/SLAMF4 Antibody (NBP2-00223) (0)
Other Available Formats
Additional 2B4/CD244/SLAMF4 Antibody (244F4) Products
Related Products by Gene
Bioinformatics Tool for 2B4/CD244/SLAMF4 Antibody (NBP2-00223)
Discover related pathways, diseases and genes to 2B4/CD244/SLAMF4 Antibody (NBP2-00223). Need help?
Read the Bioinformatics Tool Guide
for instructions on using this tool.
Blogs on 2B4/CD244/SLAMF4