XRN2 Antibody

Western Blot: XRN2 Antibody [NB100-57540] - Detection of Human and Mouse XRN2 on HeLa whole cell lysate using NB100-57540. XRN2 was immunoprecipitated by another rabbit anti-XRN2 antibody and NB100-57541.

• Reactivity: Hu, Mu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.2 mg/ml

XRN2 Antibody Summary

• Description: Novus Biologicals Rabbit XRN2 Antibody (NB100-57540) is a polyclonal antibody validated for use in WB and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: The immunogen recognized by this antibody maps to a region between residue 25 and 75 human 5'-3' exoribonuclease 2 using the numbering given in entry NP_036387.2 (GeneID 22803).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: XRN2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot 1:100-1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: TBS and 0.1% BSA
• Preservative: 0.09% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for XRN2 Antibody

• 5'-3' exoribonuclease 2
• Dhm1-like protein (mouse homolog)
• DHM1-like protein
• DHP protein
• EC 3.1.13
• EC 3.1.13.-

Background

XRN2 is a 5'-to-3' exoribonuclease involved in 3'-end mRNA processing. XRN2 is important for transcription termination and is responsible for degrading the downstream 3'-end-cleaved RNA. Recent studies show that XRN2 is recruited to 3'-end processing machinery by p54nrb/PSF. Alternate names for XRN2 include 5'-3' exoribonuclease 2, DHM1-like protein, and DHP protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: XRN2
• Entrez:
  • 22803(Human)
• Uniprot:
  • NP_036387.2(Human)