FOXE1 Antibody

Images

 
Immunohistochemistry-Paraffin: FOXE1 Antibody [NB100-1271] - Staining of paraffin embedded Human Thyroid Gland. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.
Immunohistochemistry-Paraffin: FOXE1 Antibody [NB100-1271] - Staining of paraffin embedded Human Testis. Steamed antigen retrieval with Tris/EDTA buffer pH 9, AP-staining.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, IHC-P, PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

FOXE1 Antibody Summary

Immunogen
Peptide with sequence C-AYPGGIDRFVSAM corresponding to C-Terminus according to NP_004464.2.
Localization
Nuclear
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
FOXE1
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 2 - 5 ug/ml
  • Immunohistochemistry-Paraffin 2 - 5 ug/ml
  • Peptide ELISA Detection limit 1:8000
Application Notes
WB: Preliminary experiments gave an approx. 70 kDa band in human thymus and thyroid gland lysates after 0.3 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 38.1 kDa band according to NP_004464.2. The 70 kDa band was successfully blocked by incubation with the immunizing peptide. IHC: Paraffin embedded Human Thyroid Gland shows nuclear staining in thyrocytes. Paraffin embedded Human Testis.
Publications
Read Publication using NB100-1271.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for FOXE1 Antibody

  • FKHL15HFKL5
  • forkhead box E1 (thyroid transcription factor 2)
  • forkhead box E2
  • Forkhead box protein E2
  • forkhead, drosophila, homolog-like 15
  • Forkhead-related protein FKHL15
  • HFKH4Thyroid transcription factor 2
  • TITF2HNF-3/fork head-like protein 5
  • TTF2forkhead box protein E1
  • TTF-2FOXE2

Background

This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. This gene functions as a thyroid transcription factor which likely plays a crucial role in thyroid morphogenesis. Mutations in this gene are associated with congenital hypothyroidism and cleft palate with thyroid dysgenesis. The map localization of this gene suggests it may also be a candidate gene for squamous cell epithelioma and hereditary sensory neuropathy type I.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for FOXE1 Antibody (NB100-1271)(1)

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol FOXE1
Entrez
Uniprot