XRCC2 Antibody (2H4)

Western Blot: XRCC2 Antibody (2H4) [H00007516-M01] - Analysis of XRCC2 expression in transfected 293T cell line by XRCC2 monoclonal antibody (M01), clone 2H4.Lane 1: XRCC2 transfected lysate(32 KDa).Lane 2: Non-transfected lysate.

Immunocytochemistry/Immunofluorescence: XRCC2 Antibody (2H4) [H00007516-M01] - Analysis of monoclonal antibody to XRCC2 on HeLa cell . Antibody concentration 10 ug/ml.

ELISA: XRCC2 Antibody (2H4) [H00007516-M01] - Detection limit for recombinant GST tagged XRCC2 is approximately 0.3ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA, ICC/IF
• Clone: 2H4
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

XRCC2 Antibody (2H4) Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: XRCC2 (AAH42137, 1 a.a. ~ 280 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MCSAFHRAESGTELLARLEGRSSLKEIEPNLFADEDSPVHGDILEFHGPEGTGKTEMLYHLTARCILPKSEGGLEVEVLFIDTDYHFDMLRLVTILEHRLSQSSEEIIKYCLGRFFLVYCSSSTHLLLTLYSLESMFCSHPSLCLLILDSLSAFYWIDRVNGGESVNLQESTLRKCSQCLEKLVNDYRLVLFATTQTIMQKASSSSEEPSHASRRLCDVDIDYRPYLCKAWQQLVKHRMFFSKQDDSQSSNQFSLVSRCLKSNSLKKHFFIIGESGVEFC
• Specificity: XRCC2 - X-ray repair complementing defective repair in Chinese hamster cells 2 (2H4)
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: XRCC2
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/Immunofluorescence
  • Western Blot
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for XRCC2 Antibody (2H4)

• DKFZp781P0919
• DNA repair protein XRCC2
• X-ray repair complementing defective repair in Chinese hamster cells 2
• X-ray repair cross-complementing protein 2
• X-ray repair, complementing defective, repair in Chinese hamster

Background

This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene is involved in the repair of DNA double-strand breaks by homologous recombination and it functionally complements Chinese hamster irs1, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for XRCC2 Antibody (H00007516-M01)(1)

Publication using H00007516-M01

• Shammas MA, Shmookler Reis RJ, Koley H et al. Dysfunctional homologous recombination mediates genomic instability progression in myeloma. Blood 2009;113(10):2290-2297 [PMID: 19050310]

Bioinformatics

• Gene Symbol: XRCC2
• Entrez:
  • 7516(Human)
• Uniprot:
  • AAH42137(Human)