ATRX Antibody


Orthogonal Strategies: Immunohistochemistry-Paraffin: ATRX Antibody [NBP1-83077] - Staining in human cerebral cortex and liver tissues . Corresponding ATRX RNA-seq data are presented for the same tissues.
Genetic Strategies: Western Blot: ATRX Antibody [NBP1-83077] - Analysis in A-549 cells transfected with control siRNA, target specific siRNA probe #1 and #2, using anti-ATRX antibody. Remaining relative intensity more
Immunocytochemistry/ Immunofluorescence: ATRX Antibody [NBP1-83077] - Staining of human cell line A549 shows localization to nucleoplasm and nuclear bodies. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: ATRX Antibody [NBP1-83077] - Staining of human liver shows no positivity in hepatocytes as expected.
Immunohistochemistry-Paraffin: ATRX Antibody [NBP1-83077] - Staining of human cerebral cortex shows moderate nuclear positivity in neurons and glial cells.
Immunohistochemistry-Paraffin: ATRX Antibody [NBP1-83077] - Staining of human glioma shows moderate to strong nuclear positivity in tumor cells.
Immunohistochemistry-Paraffin: ATRX Antibody [NBP1-83077] - Staining of human uterine cervix shows moderate to strong nuclear positivity in squamous epithelial cells.

Product Details

Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P, KD

Order Details

ATRX Antibody Summary

Predicted Species
Mouse (96%), Rat (97%). Backed by our 100% Guarantee.
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.


  • Immunocytochemistry/Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:500 - 1:1000
  • Immunohistochemistry-Paraffin 1:500 - 1:1000
  • Knockdown Validated
  • Western Blot 0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation/Permeabilization: PFA/Triton X-100
Control Peptide
ATRX Protein (NBP1-83077PEP)
Read Publications using
NBP1-83077 in the following applications:

  • IHC
    10 publications
  • 1 publication
  • WB
    2 publications

Reactivity Notes

Human reactivity reported in scientific literature (PMID: 22869205).

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.2) and 40% Glycerol
0.02% Sodium Azide
Immunogen affinity purified

Alternate Names for ATRX Antibody

  • alpha thalassemia/mental retardation syndrome X-linked (RAD54 (S. cerevisiae)homolog)
  • alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S.cerevisiae)
  • alpha thalassemia/mental retardation syndrome X-linked
  • ATP-dependent helicase ATRX
  • ATR2
  • DNA dependent ATPase and helicase
  • EC 3.6.1
  • EC
  • helicase 2, X-linked
  • Juberg-Marsidi syndrome
  • MGC2094
  • MRXHF1
  • RAD54 homolog
  • RAD54L
  • SFM1
  • SHS
  • transcriptional regulator ATRX
  • XH2RAD54
  • X-linked helicase II
  • X-linked nuclear protein
  • Zinc finger helicase
  • Znf-HX


ATRX is encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. The mutations of this gene are associated with an X-linked mental retardation (XLMR) syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

Species: Ce, Ch, Hu, Mu, Rt
Applications: ChIP, ICC/IF, IHC, IHC-Fr, IHC-P, IP, In vitro, KD, PLA, WB
Species: Hu
Applications: ICC/IF, KD, WB
Species: Hu
Applications: ICC, KO, WB
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, WB
Species: Hu
Applications: ICC/IF, IHC, IHC-P, WB
Species: Hu
Applications: ELISA, ICC/IF, IHC, IHC-P, S-ELISA, WB
Species: Hu, Mu
Applications: ELISA, Flow, IHC, IHC-P, WB
Species: Hu, Pm, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, IP, In vitro, KD, WB
Species: Hu
Applications: ICC/IF, IHC, IHC-P, WB
Species: Hu
Applications: WB
Species: Hu
Applications: ELISA
Species: Hu
Applications: IHC, WB
Species: Hu, Mu, Rt
Applications: IHC, IHC-P, IP, WB
Species: Mu
Applications: KO, PEP-ELISA, WB
Species: Hu, Mu
Applications: ELISA, ICC/IF, IHC, IHC-P, WB
Species: Hu, Mu, Rt, Xp(-), Ye
Applications: CyTOF-ready, ELISA, Flow-IC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, WB
Species: Hu, Mu
Applications: IP, WB
Species: Hu
Applications: CyTOF-ready, Flow, ICC/IF, IP, WB
Species: Hu, Mu
Applications: Flow, ICC/IF, IHC, IHC-P, WB
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P, KD

Publications for ATRX Antibody (NBP1-83077)(22)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 3 applications: IHC, IHC-P, WB.

Filter By Application
All Applications
Filter By Species
All Species
Showing Publications 1 - 10 of 22. Show All 22 Publications.
Publications using NBP1-83077 Applications Species
Alzoubi H, Minasi S, Gianno F et al. Alternative Lengthening of Telomeres (ALT) and Telomerase Reverse Transcriptase Promoter Methylation in Recurrent Adult and Primary Pediatric Pituitary Neuroendocrine Tumors Endocrine pathology 2022-01-06 [PMID: 34993885] (IHC) IHC
Gianno F, Antonelli M, Di Dio T, et al. Correlation Between Immunohistochemistry and Sequencing in H3G34-Mutant Gliomas The American journal of surgical pathology 2021-02-01 [PMID: 33428336]
Minasi S, Baldi C, Gianno F et al. Alternative lengthening of telomeres in molecular subgroups of paediatric high-grade glioma Childs Nerv Syst 2020-10-31 [PMID: 33128602] (IHC, Human) IHC Human
Minasi S, Baldi C, Pietsch T et al. Telomere elongation via alternative lengthening of telomeres (ALT) and telomerase activation in primary metastatic medulloblastoma of childhood J. Neurooncol. 2019-03-04 [PMID: 30830680] (IHC, Human) IHC Human
Li X, Oh S, Song H et al. A potential common role of the Jumonji C domain containing 1A histone demethylase and chromatin remodeler ATRX in promoting colon cancer. Oncol Lett 2018-09-24 [PMID: 30405805] (WB, Human) WB Human
Masayuki Yoshida, Reiko Ogawa, Hiroshi Yoshida et al. TERT promoter mutations are frequent and show association with MED12 mutations in phyllodes tumors of the breast. British Journal of Cancer 2015-09-10 [PMID: 26355235] (IHC, Human) IHC Human
Napier CE, Huschtscha LI, Harvey A et al. ATRX represses alternative lengthening of telomeres. Oncotarget 2015-06-30 [PMID: 26001292] (WB, Human) WB Human
Hayashi S, Sasaki H, Kimura T et al. Molecular-genetic and clinical characteristics of gliomas with astrocytic appearance and total 1p19q loss in a single institutional consecutive cohort. Oncotarget 2015-06-30 [PMID: 25991674] (IHC, Human) IHC Human
Fishbein L, Khare S, Wubbenhorst B et al. Whole exome sequencing identifies somatic ATRX mutations in pheochromocytomas and paragangliomas. Nat Commun 2015-01-21 [PMID: 25608029] (IHC, Human) IHC Human
Cryan JB, Haidar S, Ramkissoon LA et al. Clinical multiplexed exome sequencing distinguishes adult oligodendroglial neoplasms from astrocytic and mixed lineage gliomas. Oncotarget 2014-09-30 [PMID: 25257301] (IHC, Human) IHC Human
Show All 22 Publications.

Reviews for ATRX Antibody (NBP1-83077) (0)

There are no reviews for ATRX Antibody (NBP1-83077). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for ATRX Antibody (NBP1-83077) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies


Isotype Controls

Additional ATRX Products

Bioinformatics Tool for ATRX Antibody (NBP1-83077)

Discover related pathways, diseases and genes to ATRX Antibody (NBP1-83077). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for ATRX Antibody (NBP1-83077)

Discover more about diseases related to ATRX Antibody (NBP1-83077).

Pathways for ATRX Antibody (NBP1-83077)

View related products by pathway.

PTMs for ATRX Antibody (NBP1-83077)

Learn more about PTMs related to ATRX Antibody (NBP1-83077).

Research Areas for ATRX Antibody (NBP1-83077)

Find related products by research area.

Blogs on ATRX

There are no specific blogs for ATRX, but you can read our latest blog posts.
Download our IHC Handbook

Customers Who Bought This Also Bought

Contact Information

Product PDFs


Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.


Review this Product

Be the first to review our ATRX Antibody and receive a gift card or discount.


Gene Symbol ATRX