WWP1 Antibody

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Immunoprecipitation: WWP1 Antibody [NBP1-49713] - Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-WWP1 antibody NBP1-49713 used for IP at 3 ug/mg ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IP, WB (-)
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

WWP1 Antibody Summary

Immunogen
The immunogen for this product maps to a region between residue 300 and 350 of human WW Domain Containing E3 Ubiquitin Protein Ligase 1 using the numbering given in entry NP_008944.1 (GeneID 11059).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
WWP1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunoprecipitation 2-5 ug/mg lysate
Theoretical MW
111 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for WWP1 Antibody

  • AIP5
  • AIP5Nedd-4-like ubiquitin-protein ligase
  • atrophin-1 interacting protein 5
  • Atrophin-1-interacting protein 5
  • DKFZP434D2111
  • EC 6.3.2
  • EC 6.3.2.-
  • HSDRP1
  • NEDD4-like E3 ubiquitin-protein ligase WWP1
  • TGIF-interacting ubiquitin ligase 1
  • TIUL1
  • Tiul11
  • WW domain containing E3 ubiquitin protein ligase 1
  • WW domain-containing protein 1
  • WWP1

Background

WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. Alternative splicing of this gene generates at least 6 transcript variants; however, the full length nature of these transcripts has not been defined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Applications: IP, WB (-)

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol WWP1
Entrez
Uniprot