VPS25 Antibody [DyLight 488]

• Reactivity: Hu
• Applications: WB, IHC, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: DyLight 488

VPS25 Antibody [DyLight 488] Summary

• Immunogen: Produced in rabbits immunized with E. coli-derived Human VPS25 fragment.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: VPS25
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen and protein A Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for VPS25 Antibody [DyLight 488]

• Dermal papilla-derived protein 9
• DERP9
• DERP9hVps25
• EAP20
• EAP20FAP20
• ELL-associated protein of 20 kDa
• ESCRT-II complex subunit VPS25
• FAP20
• MGC10540
• vacuolar protein sorting 25 (yeast)
• vacuolar protein sorting 25 homolog (S. cerevisiae)
• vacuolar protein-sorting-associated protein 25

Background

"VPS25 is a component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. The ESCRT-II complex may be involved in facilitating the budding of certain RNA viruses

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: VPS25