VNN2 Antibody (3F8F8H6) [Janelia Fluor® 525]

• Reactivity: Hu
• Applications: ELISA, Flow, ELISA
• Clone: 3F8F8H6
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 525

VNN2 Antibody (3F8F8H6) [Janelia Fluor® 525] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human VNN2 (Accession#: NP_004656.2; Met 1-Ser 492).
• Specificity: No cross-reactivity in ELISA with:
  
  Human cell lysate (293 cell line)
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: VNN2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Flow Cytometry
  • Sandwich ELISA Capture
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NBP3-06441. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Reactivity Notes

No cross-reactivity in ELISA with:

Human cell lysate (293 cell line)

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for VNN2 Antibody (3F8F8H6) [Janelia Fluor® 525]

• EC 3.5.1
• EC 3.5.1.92
• FOAP-4
• Glycosylphosphatidyl inositol-anchored protein GPI-80
• GPI-80 variant protein 1
• GPI-80 variant protein 2
• GPI-80 variant protein 3
• GPI-80 variant protein 4
• GPI-80
• pantetheinase
• Protein FOAP-4
• vanin 2
• vanin-2
• Vannin 2
• vascular non-inflammatory molecule 2

Background

VNN2 product is a member of the Vanin family of proteins which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: VNN2