VLDLR Antibody (VLDLR/1337) [Janelia Fluor® 549]

• Reactivity: Hu, Rt
• Applications: IHC
• Clone: VLDLR/1337
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 549

VLDLR Antibody (VLDLR/1337) [Janelia Fluor® 549] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: Recombinant human VLDLR fragment from c-terminal (Uniprot: P98155)
• Localization: Cytoplasmic
• Isotype: IgG1 Lambda
• Clonality: Monoclonal
• Host: Mouse
• Gene: VLDLR
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NBP2-54553. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for VLDLR Antibody (VLDLR/1337) [Janelia Fluor® 549]

• CARMQ1
• CHRMQ1
• FLJ35024
• very low density lipoprotein receptor
• very low-density lipoprotein receptor
• VLDL R
• VLDL receptor
• VLDLR
• VLDL-R
• VLDLRCH

Background

VLDL (very low density lipoprotein) cholesterol is one of the three major types of cholesterol found in blood. VLDL receptor plays an essential role in triglyceride metabolism. It binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: VLDLR