Vitamin D BP Antibody (359501) [Alexa Fluor® 405]

• Reactivity: Hu
• Applications: WB
• Clone: 359501
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 405

Vitamin D BP Antibody (359501) [Alexa Fluor® 405] Summary

• Immunogen: Human plasma-derived Vitamin D BP
  Accession # P02774
• Specificity: Detects human plasma-derived Vitamin D BP in direct ELISAs and Western blots.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Vitamin D BP Antibody (359501) [Alexa Fluor® 405]

• DBP
• DBP/GC
• DBP-MAF
• DBPVDBG
• EC 6.3.1.5
• Gc
• gc-globulin
• Gc-MAF
• GRD3
• group-specific component (vitamin D binding protein)
• Group-specific component
• hDBP
• VDB
• VDBG
• VDBP
• Vitamin D BP
• vitamin D-binding alpha-globulin
• vitamin D-binding protein

Background

Vitamin D BP (VitD BP), also called VDB, DBP, Group Specific Component (Gc) or macrophage-activating factor (DBP- or Gc-MAF), is a member of the albumin family. These plasma/body fluid proteins have a conserved pattern of cysteine motifs that form binding domains. VitD BP is predominantly produced by hepatic parenchymal cells. It transports VitD, activates macrophages and osteoclasts, and enhances C5a chemotactic activity. Over 80 variant alleles have been identified, some of which correlate with osteoporosis or prostate cancer. Human and mouse VitD BP share 78% aa identity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.