Villin 1 Antibody (1D2C3)

• Reactivity: Hu
• Applications: IHC
• Clone: 1D2C3
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

Villin 1 Antibody (1D2C3) Summary

• Description: Novus Biologicals Mouse Villin 1 Antibody (1D2C3) (NBP3-45108) is a monoclonal antibody validated for use in IHC. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Raised against purified full length native Villin of chicken origin
• Specificity: Villin is One of the gelsolin family of calcium regulated actin binding proteins. Normally expressed in the brush border of epithelial cells lining the gastrointestinal tract, hepatobiliary tract and renal proximal convoluted tubules. In colorectal carcinoma, villin is highly expressed. In practice, villin can be included in the panel used for metastatic carcinoma to detect colorectal origin.
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: VIL1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin

Packaging, Storage & Formulations

• Storage: Store at 4C.
• Buffer: PBS (pH 7.4), Tween-20, 0.2% BSA
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Alternate Names for Villin 1 Antibody (1D2C3)

• D2S1471
• VIL
• villin 1
• villin-1

Background

Villin 1 encodes a member of a family of calcium-regulated actin-binding proteins. This protein represents a dominant part of the brush border cytoskeleton which functions in the capping, severing, and bundling of actin filaments. Two mRNAs of 2.7 kb and 3.5 kb have been observed; they result from utilization of alternate poly-adenylation signals present in the terminal exon. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: VIL1