TSPAN1 Antibody (819202) [Alexa Fluor™ Plus 594]

• Reactivity: Hu
• Clone: 819202
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 594

TSPAN1 Antibody (819202) [Alexa Fluor™ Plus 594] Summary

• Specificity: Detects human TSPAN1 in direct ELISAs.
• Isotype: IgG3
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for TSPAN1 Antibody (819202) [Alexa Fluor™ Plus 594]

• NET1
• NET-1
• tetraspan 1
• Tetraspan NET-1
• tetraspanin 1
• Tetraspanin TM4-C
• tetraspanin-1
• TM4C
• TM4SF
• TSPAN1
• TSPAN-1

Background

Tetraspanins (TSPAN family) are small integral proteins that contain four transmembrane domains with two different and well characterized extracellular domains. Tetraspanins are found on the plasma membrane and within various intracellular organelles and granules in nearly all cell and tissue types. They interact with one another and with other transmembrane molecules, including integrins, generating a ‘web' of interactions believed to control cell and membrane trafficking and compartmentalization. Tetraspanin-1 (TSPAN1), a 241 amino acid protein, interacts with the thiamine transporter-1 (THTR-1, SLC19A2) in human intestinal epithelial cells, linking TSPAN1 to the regulation of thiamine uptake. TSPAN1 has been found to be expressed in gastric, ovarian, colon, and other carcinomas.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.