TSLP Antibody (55N1D10) Summary
A partial recombinant TSLP protein (amino acids 27-158) was used as the immunogen for the antibody.
Protein G purified
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Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.1 mg antibody in 0.2 ml PBS containing 0.05% BSA.
0.05% Sodium Azide
Protein G purified
Alternate Names for TSLP Antibody (55N1D10)
- thymic stromal lymphopoietin
TSLP is a 159 amino acid four helix-bundle hemopoietic cytokine that signals through a heterodimeric receptor complex consisting of the human TSLP receptor and the IL-7R alpha-chain. It impacts myeloid cells and induces the release of Tcell-attracting chemokines from monocytes, enhances the maturation of CD11c+ dendritic cells, naive CD4+, and CD8+ Tcells into proallergic effectors, and primes DCs to produce large amounts of IL-12 after CD40 ligand stimulation. TSLP influences the regulation of the positive selection of regulatory Tcells and maintenance of peripheral CD4+ Tcell homeostasis. It induces allergic inflammation by directly activating mast cells and may be involved in the pathophysiology of inflammatory arthritis. TSLP is expressed in heart, liver and prostate.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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